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Global Insomnia: Affecting The Whole World, Or Just Yours?
By 41plus41
Global insomnia is simply when you have troubles falling asleep for multiple night in a row. Typically, having trouble sleeping for more than two days at a time is a sign that something is wrong with your body. Global insomnia doesn't just affect the person's sleep; it can also give them headaches and other irregular pains.

Global insomnia affects the whole body because sleep is a vital process for every part of the body. When sleeping, the mind and body has time to rest and recuperate from the day's work. This does not mean that by being asleep you will regain all energy lost throughout the day though. Many people think they are sleeping seven or eight hours per night, but the quality of their sleep is so low they can barely make it through the work day. This is common in borderline insomniacs, because they toss and turn all night, and while they don't realize it, they are not getting sufficient rest.


After multiple days of this, the body becomes weaker, the person has memory troubles, experiences headaches and their immune system weakens. Global insomnia can cause all of these problems, but is there a way to fix it?

In short: yes! Instead of being like the vast majority

Notes from Chicago
I am Lily, a new postdoc at Argonne National Lab. I'm the one who thinks she can find the Higgs boson by listening to it. Thanks Jon for letting me play on your blogIt's a walk in the parkI moved here just over a week ago to work on Atlas physics analysis (Atlas is one of the detectors at the LHC). So far the closest I have got to doing any physics here is talking about ways to limit the shock a colleague gets from the carpet-humidity-doorknob setup in his office here. But that's a start.Argonne have excellent childcare facilitiesI'm loving it here so far. It was a tricky one deciding whether to move 4000 miles from London with an 11-year-old child and no driving license. I'm glad we did.Argonne is full of smart people doing interesting physics. My PhD was on the search for the Higgs boso...
Depression Significantly Improved By Non-Invasive Therapy
Major depression is a common and disabling brain condition marked not only by the presence of depressed mood but also by its effects on sleep, energy, decision-making, memory and thoughts of death or of suicide. Major depression affects 15 million adults in the U.S., and the World Health Organization projects that by 2020, it will be the largest contributor to disability in the world after heart disease. While antidepressants have helped many to recover and resume their lives, only 30 percent of patients will experience full remission with the first medication they use... (Source: Health News from Medical News Today)
Owl Monkeys Need Moonlight As Much As A Biological Clock For Nocturnal Activity
An international collaboration led by a University of Pennsylvania anthropologist has shown that environmental factors, like temperature and light, play as much of a role in the activity of traditionally nocturnal monkeys as the circadian rhythm that regulates periods of sleep and wakefulness. The study also indicates that when the senses relay information on these environmental factors, it can influence daily activity and, in the case of a particular monkey species, may have even produced evolutionary change... (Source: Health News from Medical News Today)
Starvation keeps sleep-deprived fly brain sharp
As anyone who has ever struggled to keep his or her eyes open after a big meal knows, eating can induce sleepiness. New research in fruit flies suggests that, conversely, being hungry may provide a way to stay awake without feeling groggy or mentally challenged. (Source: ScienceDaily Headlines)
Male insomniacs at increased risk of death
Men who suffer from insomnia and who sleep for under six hours a night have an increased risk of dying, according to a US study. (Source: Nursing Times Breaking News)
Rough transition into menopause
Perimenopausal symptoms can go beyond hot flashes and may include sleep problems, psychological distress and mental lapses. Treatment options are limited, but research is ongoing.I'm 46, and there are days when it feels like I'm completely losing my mind. I misplace my car keys, struggle to remember details of recent conversations, and can't recall seemingly anybody's name. To help cope with my mental cloudiness, I always keep an extra set of keys nearby, write endless sticky notes to myself, and frequently opt for the generic "hello" over more personalized greetings. (Source: L.A. Times - Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
FDA Approves New Eye Pressure Drop Formulation
WASHINGTON (MedPage Today) -- The FDA approved a new formulation of the drug bimatoprost (Lumigan) in a 0.01% solution as a first-line treatment to reduce elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. (Source: MedPage Today Public Health)
Disturbances of the Mind
by Douwe Draaisma is a book regarding various illnesses ranging from Bonnet Syndrome to Alzheimer?s, with an entire range of brain diseases in between.  It provides an interesting narrative about how each disease came to be identified, by whom, the disease&#8217;s symptoms, and how it came to be named.  This book provides a historical background on these diseases and would be particularly useful for persons interested in the medical field.  It may also provide some insights on the disease for people with family members or friends who may unfortunately be afflicted.  This book, while interesting, is not deemed a page-turner initially.  However, it continues to pique the reader?s interest and even becomes quite fascinating in the latter chapters.  While each disease is covered in ...
Audio » John Piacentini on Treating Tics Associated With Tourette Syndrome
Dr. John Piacentini of UCLA talks about CBIT, a new therapy that treats tics associated with Tourette's Syndrome (Source: National Institute of Mental Health)
Marijuana better than pharmaceuticals at treating chronic pain, improving mood
(NaturalNews) Experts from different persuasions often argue about the alleged benefits of using marijuana for pain relief, but a new study out of McGill University Health Centre (MUHC) and McGill University (MU) has conclusively found that cannabis, the genus name for marijuana, is better than pharmaceutical drugs at relieving chronic neurological pain, and without all the harmful side effects.Appearing in the latest issue of the Canadian Medical Association Journal, the study reveals that tetrahydrocannabinol (THC), the active ingredient in marijuana that gives it psychoactive and analgesic properties, is linked to relieving chronic pain, improving mood and inducing better sleep in those with severe neurological pain. Patients who took a single inhalation of marijuana smoke three times a...
Treatment Options for Parasomnias
Parasomnias are undesirable physical or experiential events that occur in and around sleep. Treatments include reassurance in some cases, various forms of cognitive-behavioral therapy (CBT), and pharmacologic agents. Cognitive restructuring, imagery rehearsal, relaxation, hypnosis, desensitization, and anticipatory awakenings are some of the common CBT and nonpharmacologic interventions. Medications that are used belong to a wide variety of pharmacologic classes, such as ?-blockers (prazosin), tricyclic antidepressants (imipramine and clomipramine), selective serotonin reuptake inhibitors, benzodiazepines (diazepam and clonazepam), anticonvulsants (topiramate and gabapentin), desmopressin acetate, and anticholinergic agents (oxybutynin and tolterodine). Data on efficacy are only available...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Guidelines for insomnia, sleep disorders
LONDON, Sept. 4 (UPI) -- The British Association for Psychopharmacology has created guidelines to help psychiatrists and physicians treat those with sleep problems, researchers say. Sleep disorder - Insomnia - Health - Conditions and Diseases - United States (Source: Health News - UPI.com)
Guidelines for sleep problems offered
LONDON, Sept. 4 (UPI) -- The British Association for Psychopharmacology has created guidelines to help psychiatrists and physicians treat those with sleep problems, researchers say. Sleep disorder - Health - Conditions and Diseases - Psychiatrist - United States (Source: Health News - UPI.com)
Predicting Obstructive Sleep Apnea Among Women Candidates for Bariatric Surgery
Journal of Women's Health , Vol. 0, No. 0. (Source: Journal of Women)
FDA Approves Bimatoprost 0.01% Eye Drops For Elevated Intraocular Pressure
FDA has approved bimatoprost 0.01% ophthalmic solution for the first-line treatment of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Medscape Medical News (Source: Medscape Pharmacist Headlines)
Life with Infertility is Hectic!
Whether your infertility is newly diagnosed or a condition for which you've received long term treatment, "hectic" is likely to be a familiar word in your vocabulary. However, for you, the frustrating aspect of "hectic" is that it is punctuated by periods of waiting -- for test results, for procedures, for consultations, and -- of course-- for a pregnancy. In my book When You're Not Expecting, I refer to this as the period when your life is on hold.So, what's to do when you feel as if you're dancing to the tune of your infertility specialist, clinic schedules and medical procedures? Undoubtedly you will search for ways to lift your spirits, distract yourself from disappointing news, consider new options and nurture your relationships. These are all components of emotional resilience, a fam...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Insomnia Means More Than A Bad Night's Sleep
A new study says men who reported having insomnia and who slept less than 6 hours a night were four times more likely to die over a 14-year period when compared to men who reported sleeping well. Sleep researcher and psychiatrist Alexandros Vgontzas explains the finding.&raquo; E-Mail This&nbsp;&nbsp;&nbsp;&nbsp; &raquo; Add to Del.icio.us (Source: NPR Health and Science)
Mammalian Telomeric DNA Suppresses Endotoxin-induced Uveitis [Dna and Chromosomes]
This study demonstrates the selective down-regulatory role of suppressive ODN after (i) local or (ii) systemic treatment in EIU-induced rabbits and mice. Our results indicate that suppressive ODN down-regulate at both the transcript and protein levels of several proinflammatory cytokines and chemokines as well as nitric oxide and co-stimulatory surface marker molecules when administrated prior to, simultaneously with, or even after LPS challenge, thereby significantly reducing ocular inflammation in both rabbit and mouse eyes. These findings strongly suggest that suppressive ODN is a potent candidate for the prevention of uveitis and could be applied as a novel DNA-based immunoregulatory agent to control other autoimmune or autoinflammatory diseases. (Source: Journal of Biological Chemistr...
New guidelines to ease sleepless nights
Insomnia and other sleep disorders are very common, yet are not generally well understood by doctors and other health care professionals. Now the British Association for Psychopharmacology (BAP) has published new guidelines to guide psychiatrists and physicians caring for those with sleep problems. The research, led by Dr Sue Wilson, Senior Research Fellow in Psychopharmacology at the University of Bristol, provides a comprehensive guide on the best current treatments for sleep disorders to clinicians, who are managing patients in primary or secondary medical care. (Source: University of Bristol news)
A Review of the Surgical Treatment Options for the Obstructive Sleep Apnea/Hypopnea Syndrome Patient
(Source: Military Medicine)
Easing Sleepless Nights: New Guidelines
Insomnia and other sleep disorders are very common, yet are not generally well understood by doctors and other health care professionals. Now the British Association for Psychopharmacology (BAP) has released up-to-the-minute guidelines in the Journal of Psychopharmacology, published by SAGE, to guide psychiatrists and physicians caring for those with sleep problems... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Pivotal Study Finds Link Between PTSD And Dementia
Results of a study reported in the September issue of the Journal of the American Geriatrics Society suggest that Veterans with post-traumatic stress disorder (PTSD) have a greater risk for dementia than Veterans without PTSD, even those who suffered traumatic injuries during combat. Exposure to life threatening events, like war, can cause PTSD, and there are high rates among veterans. PSTD includes symptoms such as avoiding things or people that remind a person of the trauma, nightmares, difficulty with sleep, and mood problems... (Source: Health News from Medical News Today)
Teens Who Sleep Less Eat More Fatty Foods And Snacks
A study in the Sept. 1 issue of the journal Sleep shows that teens who slept less than eight hours per weeknight ate higher proportions of fatty foods and snacks than adolescents who slept eight hours or more. The results suggest that short sleep duration may increase obesity risk by causing small changes in eating patterns that cumulatively alter energy balance, especially in girls... (Source: Health News from Medical News Today)
Moonstruck primates: Owl monkeys need moonlight as much as a biological clock for nocturnal activity
(University of Pennsylvania) An international collaboration led by a University of Pennsylvania anthropologist has shown that environmental factors, like temperature and light, play as much of a role in the activity of traditionally nocturnal monkeys as the circadian rhythm that regulates periods of sleep and wakefulness. (Source: EurekAlert! - Biology)
Sleep lack, mental stress in ages 17-24
SYDNEY, Sept. 2 (UPI) -- Researchers in Australia say they have found a link between shorter sleep times and higher risk of mental distress in young adults. Health - Stress - Conditions and Diseases - Sleep Disorders - Research (Source: Health News - UPI.com)
Men With Insomnia May Have Higher Risk of Death
Men with insomnia have a fourfold higher death rate than those who sleep at least 6 hours a night, a 14-year study finds. It's not yet clear whether women with insomnia also die sooner. (Source: WebMD Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Insomnia and its correlates in a representative sample of the Greek population
Conclusions: The present study confirms most findings reported from other developed countries around the world regarding the high prevalence of insomnia problems in the general population and their association with several sociodemographic and health-related predisposing factors. These results further indicate the need for more active interventions on the part of physicians who should suspect and specifically ask about such symptoms. (Source: BMC Public Health - Latest articles)
Quantification of vestibular-induced eye movements in zebrafish larvae
Conclusions: Our results provide evidence for a functional vestibulo-oculomotor circuit in 72 hpf zebrafish larvae that relies upon sensory input from anterior/utricular otolith organs. (Source: BioMed Central)
Human ocular carotenoid-binding proteins
Binxing Li, Preejith Vachali, Paul S. Bernstein (Perspective from Photochem. Photobiol. Sci.) Binxing Li, Photochem. Photobiol. Sci., 2010, DOI: 10.1039/c0pp00126k To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Photochem. Photobiol. Sci. latest articles)
Circadian Rhythms and Body Cycles
Circadian Rhythms: Their role and dysfunction in affective disorder. (Source: Disabled World)
Non-invasive therapy significantly improves depression, UCLA researchers say
Major depression is a common and disabling brain condition marked not only by the presence of depressed mood but also by its effects on sleep, energy, decision-making, memory and thoughts of death or of suicide. &nbsp; Major depression&nbsp;affects 15 million adults in the U.S., and the World Health Organization projects that by 2020, it&nbsp;will be the largest contributor to disability in the world after heart disease. &nbsp; While antidepressants have helped many to recover and resume their lives, only 30 percent of patients will experience full remission with the first medication they use. Patients typically move on to try a series of other antidepressants. A persistent problem with such drugs has been major side effects, including obesity, sexual dysfunction, fatigue, drowsiness and n...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
For teens, too little sleep may equal too many snacks
All those late nights spent trolling Facebook, texting friends, and cramming for tests may be taking a toll on teenagers' diets, a new study suggests. (Source: CNN.com - Health)
How to Get to Sleep on Sleepless Nights - New Guidelines
New guidelines to ease sleepless nights - Insomnia and other sleep disorders are very common, yet are not generally well understood by doctors and other health care professionals. (Source: Disabled World)
Short Sleep And Chronic Insomnia Linked To Four-Fold Risk Of Early Death In Men
US researchers found that short sleep and insomnia was linked to a four times higher risk of early death in men; they urged public health policy makers to emphasize earlier diagnosis and treament of chronic insomnia. You can read how researchers from the Pennsylvania State University College of Medicine, in Hershey, Pennsylvania, came to these findings in a paper they wrote that was published on 1 September in the journal SLEEP... (Source: Health News from Medical News Today)
Drug-induced sleep endoscopy: conventional versus target controlled infusion techniques?a randomized controlled study
Abstract&nbsp;&nbsp;Understanding the sites of pharyngeal collapse is mandatory for surgical treatment decision-making in obstructive sleep-apnea-hypopnea syndrome patients. Drug-induced sleep endoscopy (DISE) allows for the direct observation of the upper airway during sedative-induced sleep. In order to re-create snoring and apnea patterns related to a spontaneous sleep situation, the authors used a target-controlled infusion (TCI) sleep endoscopy (DISE-TCI), comparing this technique to conventional DISE, in which sedation was reached by a manual bolus injection. The authors conducted a prospective, randomized, unicenter study. The apneic event observation and its correlation with pharyngeal collapse patterns is the primary endpoint; secondary endpoints are defined as stability and ...
Too little sleep bad for teenagers' diets: study
CHICAGO (Reuters) - Teenagers who sleep less than eight hours a night on weeknights eat more fatty foods and snacks than those who get more than eight hours of sleep a night, U.S. researchers said on Wednesday. (Source: Reuters: Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Cannabis for nerve pain studied
?Smoking cannabis from a pipe can significantly reduce chronic pain in patients with damaged nerves,? reported the BBC. It added that improvements in sleep and anxiety were seen. (Source: Neurological Conditions Specialist Library)
Better Than Coffee
Dear Health Conscious Reader, People love this stuff, so in case you missed this? I have something that will electrify you? It?s even better than coffee. When I was hiking through the Amazon Rain Forest last year, I had a first-hand experience with a remarkable healing herb. This rain forest herb gives you lasting energy ? without the crash. Sacred to the nearby Guarani tribe, it was literally a gift  the gods. According to tribal folklore, the Indians of the Amazon River Basin have been using it to prevent fatigue and increase physical endurance since before recorded history. I took it in the early morning before we hit the trail. After 18 hours through the jungles of Peru my mind was crystal clear and I had no feeling of fatigue. Looking back, I had covered 15 miles of rugged te...
A novel method of culturing human oral mucosal epithelial cell sheet using post-mitotic human dermal fibroblast feeder cells and modified keratinocyte culture medium for ocular surface reconstruction
Conclusion This novel culture method using dermal fibroblasts and pharmaceutical agents provides a safe cell processing system without xenogenic feeder cells for ocular surface reconstruction. (Source: British Journal of Ophthalmology)
The prevalence and causes of visual impairment in indigenous Australians within central Australia: the Central Australian Ocular Health Study
Conclusion This study indicates that bilateral visual impairment and blindness are, respectively, 25.1% and 3.6% among indigenous Australians, four to seven times higher than among the non-indigenous Australian population. Trachoma is the leading cause of bilateral blindness after refractive error and cataract. (Source: British Journal of Ophthalmology)
Long-term ocular complications in aphakic versus pseudophakic eyes of children with juvenile idiopathic arthritis-associated uveitis
Conclusion With maximum control of perioperative inflammation and intensive follow-up, the implantation of an intraocular lens in well-selected eyes of children with JIA-associated uveitis is not associated with an increased risk of ocular hypertension, secondary glaucoma, cystoid macular oedema and optic disc swelling and showed better visual results up to and including 7&nbsp;years after cataract extraction. (Source: British Journal of Ophthalmology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Sampling and measurement methods for a study of childhood refractive error in a UK population
Conclusions The study design, sample size and methodology will ensure accurate measures of the prevalence of refractive errors in the target population and will facilitate comparisons with other population-based refractive data. (Source: British Journal of Ophthalmology)
Eye movement recordings to investigate a supranuclear component in chronic progressive external ophthalmoplegia: a cross-sectional study
Conclusions This study does not support a supranuclear component to the ophthalmoplegia of CPEO, although the increased latencies observed may warrant further investigation. (Source: British Journal of Ophthalmology)
Delayed adjustable sutures: a multicentred clinical review
Conclusions This large multicentred series characterises the closed conjunctival delayed adjustable suture technique for the correction of strabismus. It may present some significant advantages to more traditional adjustable suture techniques. (Source: British Journal of Ophthalmology)
New Guidelines Issued for Insomnia and Other Sleep Disorders
The British Association for Psychopharmacology has issued a consensus statement on evidence-based treatment of insomnia, parasomnias, and circadian rhythm disorders. Medscape Medical News (Source: Medscape Today Headlines)
Influence of genotype on dopamine transporter availability in human striatum and sleep architecture
Abstract: Genetic variants may modulate dopamine transporter (DAT) availability in the brain. A polymorphism within the intron 8 of the DAT1 gene was evaluated in 27 healthy men. No correlation between Int8 VNTR and either the inter-individual variability of the sleep architecture, or the DAT availability, as measured by single photon emission computed tomography (SPECT) and [99mTc]TRODAT-1 was observed. (Source: Psychiatry Research)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Excessive daytime sleepiness in depressed women
Abstract: Excessive daytime sleepiness (EDS) is a symptom with high public health importance. Within psychiatric settings, depression is the most significant risk factor for EDS; however, this relationship has not been clearly detailed. The aim of this study was to describe the quality of sleep of depressed patients with and without EDS and to investigate the association between EDS and depression severity. A cross-sectional study with 78 female depressed outpatients (34.17±11.37years; range 18?60) was performed. The Epworth Sleepiness Scale, the Athens Insomnia Scale, the Pittsburgh Sleep Quality Index, and the Hamilton Rating Scale for Depression (HRSD) were administered. Patients were classified in two groups: with (43.5%) and without (56.5%) EDS. There were no differences with regar...
Namibia: NBL Honours Eye Surgeon
Dr Helena Ndume is the Namibia Breweries Limited (NBL) Ambassador for the month of August - for almost single-handedly instituting a unique medical scheme which offers blind poverty-stricken Namibians eye surgery and intra-ocular lens implants free of charge. (Source: AllAfrica News: Health and Medicine)
Understanding the relationships between health outcomes in generalized anxiety disorder clinical trials
Conclusion&nbsp;&nbsp;This adapted Wilson?Cleary model for health outcomes validated in GAD should improve the understanding and usefulness of health status measurements in this condition and increase the applications of this model to other clinical trial data. Content Type Journal ArticleDOI 10.1007/s11136-010-9734-1Authors Kathleen W. Wyrwich, United BioSource Corporation, 7101 Wisconsin Ave. Suite 600, Bethesda, MD 20814, USANeesha Harnam, United BioSource Corporation, 7101 Wisconsin Ave. Suite 600, Bethesda, MD 20814, USAJulie C. Locklear, AstraZeneca Pharmaceuticals LP, Wilmington, Delaware USAHenrik Svedsäter, AstraZeneca R&D, Mölndal, SwedenDennis A. Revicki, United BioSource Corporation, 7101 Wisconsin Ave. Suite 600, Bethesda, MD 20814, USA Journal Quality o...
Chronic Insomnia With Objectively Measured Short Sleep Duration Is Associated With Increased Mortality In Men
A study in the Sept. 1 issue of the journal SLEEP found an elevated risk of death in men with a complaint of chronic insomnia and an objectively measured short sleep duration. The results suggest that public health policy should emphasize the diagnosis and appropriate treatment of chronic insomnia. Compared to men without insomnia who slept for six hours or more, men with chronic insomnia who slept for less than six hours were four times more likely to die during the 14-year follow-up period (odds ratio = 4.33)... (Source: Health News from Medical News Today)
Allergan Receives FDA Approval For LUMIGAN(R) 0.01% As First-Line Therapy Indicated For The Reduction Of Elevated Intraocular Pressure In Glaucoma
Allergan, Inc. (NYSE:AGN) announced the United States Food and Drug Administration (FDA) has approved LUMIGAN® (bimatoprost ophthalmic solution) 0.01% as a first-line therapy indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. LUMIGAN® 0.01% is an optimized reformulation of LUMIGAN® (bimatoprost ophthalmic solution) 0.03%. "The approval of LUMIGAN® 0... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Sleep-Deprived Teens Eat More Fat, Study Finds
Title: Sleep-Deprived Teens Eat More Fat, Study FindsCategory: Health NewsCreated: 9/1/2010 10:10:00 AMLast Editorial Review: 9/2/2010 (Source: MedicineNet Sleep General)
To
Title: To Not (Source: MedicineNet Sleep General)
Sleep-Deprived Teens Eat More Fat, Study Finds
Title: Sleep-Deprived Teens Eat More Fat, Study FindsCategory: Health NewsCreated: 9/1/2010 10:10:00 AMLast Editorial Review: 9/2/2010 (Source: MedicineNet Diabetes General)
Sleep-Deprived Teens Eat More Fat, Study Finds
Title: Sleep-Deprived Teens Eat More Fat, Study FindsCategory: Health NewsCreated: 9/1/2010 10:10:00 AMLast Editorial Review: 9/2/2010 (Source: MedicineNet Senior Health General)
Amaurosis after spine surgery: survey of the literature and discussion of one case
Abstract&nbsp;&nbsp;Postoperative vision loss (POVL) associated with spine surgery is a well known, albeit very rare complication. POVL incidence after spinal surgery ranges from 0.028 to 0.2%; however, due to the increase in number and duration of annual complex spinal operations, the incidence may increase. Origin and pathogenesis of POVL remain frequently unknown. A 73-year-old patient presented with lumbar disc herniation with associated neurological deficits after conservative pre-treatment at a peripheral hospital. Known comorbidities included arterial hypertension, moderate arterial sclerosis, diabetes mellitus type 2, mildly elevated blood lipids and treated prostate gland cancer. During lumbar spine surgery in modified prone position the patient presented with an acute episo...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Autoimmune disease in mothers with the FMR1 premutation is associated with seizures in their children with fragile X syndrome
In conclusion, autoimmune disease in carrier mothers was not associated with the presence of ASD in their children. However, seizures and tics were significantly increased in children of mothers with autoimmune disease. This suggests a potential new mechanism of seizure and tic exacerbation in FXS related to an intergenerational influence from autoimmunity in the carrier mother. Content Type Journal ArticleDOI 10.1007/s00439-010-0882-8Authors Weerasak Chonchaiya, Medical Investigation of Neurodevelopmental Disorders (MIND) Institute, University of California Davis Health System, 2825 50th Street, Sacramento, CA 95817, USAFlora Tassone, Medical Investigation of Neurodevelopmental Disorders (MIND) Institute, University of California Davis Health System, 2825 50th Street, Sacramento...
The developmental impact of prenatal stress, prenatal dexamethasone and postnatal social stress on physiology, behaviour and neuroanatomy of primate offspring: studies in rhesus macaque and common marmoset
Conclusions&nbsp;&nbsp;Perinatal stress-related environmental events exert short- and long-term effects on HPA function, behaviour and brain status in rhesus macaque and common marmoset. The mechanisms mediating the enduring effects remain to be elucidated, with candidates including increased basal HPA function and epigenetic programming. Content Type Journal ArticleDOI 10.1007/s00213-010-1989-2Authors Christopher R. Pryce, Behavioural Neurobiology Laboratory, Swiss Federal Institute of Technology Zürich, Schwerzenbach, SwitzerlandYves Aubert, Behavioural Neurobiology Laboratory, Swiss Federal Institute of Technology Zürich, Schwerzenbach, SwitzerlandClaudia Maier, Behavioural Neurobiology Laboratory, Swiss Federal Institute of Technology Zürich, Schwerzenbach, SwitzerlandP...
Increased risk of death in men with insomnia and a short sleep duration
Men with chronic insomnia who slept for less than six hours were four times more likely to die during the 14-year follow-up period, according to a new study. Results were adjusted for potential confounders such as body mass index, smoking status, depression and obstructive sleep apnea. Further adjustments for hypertension and diabetes had little effect on the elevated mortality risk. No significant mortality risk was found in women with insomnia and a short sleep duration of less than six hours. (Source: ScienceDaily Headlines)
Ketoprofen pharmacokinetics, efficacy, and tolerability in pediatric patients.
In conclusion, ketoprofen is effective and well tolerated in children for the control of post-surgical pain and for the control of pain and fever in inflammatory conditions. PMID: 20799760 [PubMed - in process] (Source: Paediatric Drugs)
New guidelines to ease sleepless nights
(SAGE Publications UK) Insomnia and other sleep disorders are very common, yet are not generally well understood by doctors and other health care professionals. Now the British Association for Psychopharmacology has released up-to-the-minute guidelines in the Journal of Psychopharmacology, published by SAGE, to guide psychiatrists and physicians caring for those with sleep problems. (Source: EurekAlert! - Medicine and Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Durezol® (Difluprednate Ophthalmic Emulsion 0.05%) Compared with Pred Forte® 1% Ophthalmic Suspension in the Treatment of Endogenous Anterior Uveitis
Journal of Ocular Pharmacology and Therapeutics , Vol. 0, No. 0. (Source: Journal of Ocular Pharmacology and Therapeutics)
Men who don't sleep may die sooner
HERSHEY, Pa., Sept. 1 (UPI) -- Men who complain of chronic insomnia and who sleep less than 6 hours a night have an increased risk of dying, U.S. researchers say. Insomnia - Sleep disorder - Health - Conditions and Diseases - United States (Source: Health News - UPI.com)
More sleep leads to more teen weight loss
BOSTON, Sept. 1 (UPI) -- A U.S. doctor suggests teens wishing to lose weight consider getting enough sleep -- 8 hours or more a night. Weight loss - Health - United States - Shopping - Support Groups (Source: Health News - UPI.com)
Sleep-deprived teenagers 'triple chances of mental illness' by spending nights online
Young people who rob themselves of sleep by spending all night surfing the internet and playing computer games are tripling their chances of developing a mental illness, according to research. (Source: Telegraph Health)
Too little sleep bad for teenagers' diets: study
CHICAGO (Reuters) - Teenagers who sleep less than eight hours a night on weeknights eat more fatty foods and snacks than those who get more than eight hours of sleep a night, U.S. researchers said on Wednesday. (Source: Reuters: Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Later school times lead to less snoring, more studying
With classes that start as early as 7 a.m. and buses that pull up long before sunrise, some 80 percent of American kids in grades 6 through 12 are falling short of sleep recommendations during the school year, according to research by the National Sleep... (Source: OrlandoSentinel: Medical Research)
Desperate for a Cure, One Physician Heals Himself
Frustrated by lack of interest from drug companies, a Belgian doctor pursues own research to help cure his myasthenia gravis, a rare neurological condition. (Source: WSJ.com: Health)
Online night-owls 'risk mental illness': Sleepless nights blamed for rise in teen depression
Young people who become sleep deprived by using the internet into the small hours are much more likely to become mentally ill in later life, research shows. (Source: the Mail online | Health)
Loving and Losing
Light blue eyes peered out at me from a fringe of dark lashes. "We were so perfect together, her sensuous smell, her dancing eyes, her exquisite face, her sumptuous body! She's so delicate, innocent, and I feel so protective with her." Mark was clearly smitten.I was curious about the nature of his ardor. "What else do you love about her?" I inquired."Caroline is so sweet, soft, feminine in her ways. We had this incredible spiritual and emotional connection. I don't get it. Why'd she end it?" Dreamy eyes turned into tortuous question marks.To which I posed yet another question. "What did she tell you?"Like all of you, Mark had all the answers, not me. "She said she needed to work on herself so she'd be more independent.":"I see." I commented.And he went on with "Here's the thing. There's th...
When Texting Becomes an Addiction
Excessive Texting Can Become Obession; Could Lead to Lack of Eating, Isolation and Sleep Deprivation (Source: Health News: CBSNews.com)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
When Texting Becomes an Addiction
Excessive Texting Can Become Obession; Could Lead to Lack of Eating, Isolation and Sleep Deprivation (Source: Health News: CBSNews.com)
Sleepy teens eat more fat: study
Teens who sleep less than eight hours on weeknights tend to eat more fatty foods than those who doze longer, researchers have found. (Source: CBC | Health)
To Not Sleep, Perchance to Shorten Your Life
Study finds insomniac men were more likely to die earlier (Source: The Doctors Lounge - Neurology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
When Texting Becomes an Addiction
Excessive Texting Can Become Obession; Could Lead to Lack of Eating, Isolation and Sleep Deprivation (Source: Health News: CBSNews.com)
To Not Sleep, Perchance to Shorten Your Life
Study finds insomniac men were more likely to die earlier Source: HealthDay Related MedlinePlus Pages: Men's Health, Sleep Disorders (Source: MedlinePlus Health News)
Are You a Texting Addict?
Excessive Texting Can Become Unhealthy Obession; Could Leads to Lack of Eating, Isolation and Sleep Deprivation (Source: Health News: CBSNews.com)
Less Than 5 Hours Sleep Linked To Higher Mental Illness Risk
Young healthy adults aged between 17 and 24 years who get less than an average of 5 hours' sleep each night have three times the risk of developing a mental illness compared to individuals of the same age who sleep eight to nine hours every night, according to a study carried out by the George Institute on Global Health, published in the medical journal Sleep. Researchers at the George Institute for Global Health carried out a survey involving 20,822 individuals aged 17-24 years across New South Wales, Australia, identified through the state vehicle licensing authority... (Source: Health News from Medical News Today)
Death risk from insomnia unclear
Conclusion This study has found that in middle-aged men, self-reported insomnia and objectively measured short sleep duration was associated with a greater risk of death during the 14-year follow-up period, compared with men who did not have insomnia or short sleep duration. However, these findings require careful interpretation and do not prove that insomnia increases the risk of early death: The study has an important limitation in that it is a secondary analysis of a study set up to assess the age distribution of people with sleep-disordered breathing. As such, the participants were not selected at random. All of them had a higher risk of sleep-disordered breathing, and the women had markedly higher BMIs. These factors may affect both mortality risk and insomnia. Therefore, the resul...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Back to school: college drinking concerns
It was recently reported that the University of New Hampshire is considering offering an amnesty program for underage students caught drinking on campus, in an effort to reduce alcohol related injury on school grounds. Those who support the program say students are drinking anyway, if the fear of suspension is removed they may be less inclined to be left alone when drunk, thereby reducing the risk of injury. Researchers at Children?s Hospital Boston disagree. A recently released study by the Children?s Center for Adolescent Substance Abuse Research (CeASAR) shows colleges with strictly enforced alcohol policies have fewer cases of underage drinking and dangerous binge drinking. Many young people are currently gearing up for an upcoming year at college. While at school it?s almost in...
Less is More: Study Shows That Teens Who Sleep Less Eat More Fatty Foods and Snacks
September 1, 2010 (EurekAlert) - A study in the Sept. 1 issue of the journal Sleep shows that teens who slept less than eight hours per weeknight ate higher proportions of fatty foods and snacks than adolescents who slept eight hours or more. The results suggest that short sleep duration may increase obesity risk by causing small changes in eating patterns that cumulatively alter energy balance, especially in girls. read more (Source: Diabetes News from dLife.com)
Sleep-Deprived Teens Eat More Fat, Study Finds
Those who get less than eight hours a night at risk for obesity, experts say (Source: The Doctors Lounge - Neurology)
The Detoxifier Found in Every Emergency Room
I want to tell you about something that could one day save your life. I recommend you keep some in your medicine cabinet at all times. Hospitals consider this so effective they carry it in emergency rooms to treat poison victims. Taken orally it has the ability to extract and neutralize many more times its own weight in gases, heavy metals, toxins, poisons, and other chemicals. Just a tiny amount the size of a postage stamp can absorb up to 4 tennis courts worth of toxins! It saves thousands of lives every year. But it does so much more. I?m talking about activated charcoal. Activated charcoal keeps poisons and toxins from being absorbed into your body. Taking activated charcoal can help wipe out decades of toxic heavy metals that may have been accumulating in your body. Harmful me...
Covidien Completes Sale Of Sleep Therapy Product Line
Covidien (NYSE: COV), a leading global provider of healthcare products, today announced that it has completed the previously announced sale of its Sleep Therapy continuous positive airway pressure (CPAP) and Bi-level products to PH Invest, a privately held company located in Luxembourg. Financial terms of the transaction were not disclosed... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Sleep-Deprived Teens Eat More Fat
Those who get less than eight hours a night at risk for obesity, experts say Source: HealthDay Related MedlinePlus Pages: Obesity in Children, Sleep Disorders, Teen Health (Source: MedlinePlus Health News)
Insomnia and a short sleep duration
A study in the Sept. 1 issue of the journal SLEEP found an elevated risk of death in men with a complaint of chronic insomnia and an objectively measured short sleep duration. The results suggest that public health policy should emphasize the diagnosis and appropriate therapy of chronic insomnia........ (Source: Medicineworld.org: New Article Alert)
Supersymmetry - the end of the line | Jon Butterworth and Herbi Dreiner
Just before this blog moved to the Guardian, I wrote about a supersymmetry meeting I attended. Now my theory pal who organised it chips inIn case you missed it, I wrote about a conference on supersymmetry I went to last week, just before this blog moved home. I also gave some reasons why supersymmetry might, or might not, be seen as an attractive extension of the Standard Model of particle physics, given that there is no experimental evidence for it yet.Now my theory friend Herbi Dreiner, who I used to work with when I was a student and who organised the Bonn meeting, has given his view. Since I know there are heaps of supersymmetry fans out there, I thought I should bring it to your attention:The conference on "Supersymmetry and the Unification of Fundamental Interactions", which my coll...
Improving Ocular Disease Screening By LED Illumination Of The Eye
A new imaging system using six different wavelengths to illuminate the interior of the eyeball (ocular fundus) may pave the way for doctors to easily screen patients for common diseases of the eye, such as age-related macular degeneration and diabetic retinopathy. The system is described in the journal Review of Scientific Instruments, which is published by the American Institute of Physics... (Source: Health News from Medical News Today)
Renin-angiotensin-aldosterone system in patients with sleep apnoea: prevalence of primary aldosteronism
Obstructive sleep apnoea (OSA) is a sleep disorder characterized by recurrent episodes of oxygen desaturation during sleep, representing an independent risk factor for cardiovascular disease, such as myocardial infarction, stroke, congestive heart failure and resistant hypertension. Several neurohormonal mechanisms have been suggested to account for blood pressure increases, such as sympathetic nervous system hyperactivity, oxidative stress, renin&mdash;angiotensin&mdash;aldosterone system (RAAS) activation, endothelin system activation, and endothelial dysfunction. The aim of this study was to evaluate the behaviour of RAAS and the presence of primary aldosteronism (PA) in these patients and possible correlations between RAAS and the severity of OSA. From October 2007 to November 2008 we ...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Being Hungry May Provide A Way To Stay Awake Without Feeling Groggy Or Mentally Challenged
As anyone who has ever struggled to keep his or her eyes open after a big meal knows, eating can induce sleepiness. New research in fruit flies suggests that, conversely, being hungry may provide a way to stay awake without feeling groggy or mentally challenged. Scientists at Washington University in St. Louis found that starvation allows the need for nourishment to push aside the need for sleep. Like humans and rats, fruit flies cannot survive without sleep... (Source: Health News from Medical News Today)
The Future of SLEEP at www.journalsleep.org
(Source: Sleep)
Sleep Homeostasis: Finding Odysseus among the Mnesteres
Commentary on Mongrain et al. Separating the contribution of glucocorticoids and wakefulness to the molecular and electrophysiological correlates of sleep homeostasis. SLEEP 2010;33:1147-1157. (Source: Sleep)
Metabolic Disease in Sleep Disordered Breathing: Puberty! Puberty!
Commentary on Kelly et al. Catecholamines, adiponectin, and insulin resistance as measured by HOMA in children with obstructive sleep apnea. SLEEP 2010;33:1185-1191. (Source: Sleep)
Short Sleep Duration Promoting Overconsumption of Food: A Reward-Driven Eating Behavior?
Commentary on Weiss et al. The association of sleep duration to adolescents&rsquo; fat and carbohydrate consumption. SLEEP 2010;33:1201-1209. (Source: Sleep)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Short Sleep Duration in Prevalent and Persistent Psychological Distress in Young Adults: The DRIVE Study
Conclusions: Self-reported shorter sleep duration is linearly associated with prevalent and persistent psychological distress in young adults. In contrast, only the very short sleepers had a raised risk of new onset of distress. Different approaches to sleep duration measurement yield different results and should guide any interventions to improve subjective sleep duration in young adults. Keywords: Sleep, psychological distress, cohort, young adult (Source: Sleep)
Separating the Contribution of Glucocorticoids and Wakefulness to the Molecular and Electrophysiological Correlates of Sleep Homeostasis
Conclusions: Our findings indicate that corticosterone contributes to the sleep-deprivation&ndash;induced changes in brain transcriptome that have been attributed to wakefulness per se. The study identified 78 transcripts that respond to sleep loss independent of corticosterone and time of day, among which genes involved in neuroprotection prominently feature, pointing to a molecular pathway directly relevant for sleep function. Keywords: Sleep regulation, corticosterone, neuroprotection, microarray, microRNA (Source: Sleep)
Insomnia with Short Sleep Duration and Mortality: The Penn State Cohort
Conclusions: Insomnia with objective short sleep duration in men is associated with increased mortality, a risk that has been underestimated. Keywords: Insomnia, short sleep duration, mortality, population-based study (Source: Sleep)
Determining Sleep Quality in Children with Sleep Disordered Breathing: EEG Spectral Analysis Compared with Conventional Polysomnography
Conclusions: Both conventional scoring and EEG spectral analysis indicated only minor disruptions to sleep quality in children with SDB when assessed across the night, in any specific hour of the night, or in any specific sleep stage. These results suggest that reduced daytime functioning previously reported in children with SDB may not be due to sleep disruption. We speculate that in children, in contrast to adults, a stronger sleep drive may preserve sleep quality even in severe SDB. Keywords: Pediatric, children, sleep, apnea, sleep quality, spectral analysis, EEG (Source: Sleep)
The Relative Impact of Obstructive Sleep Apnea and Hypertension on the Structural and Functional Changes of the Thoracic Aorta
Conclusions: Hypertension is a common finding in male AMI patients with OSA. In these patients, increased afterload from systemic hypertension rather than mechanical stress on the aortic wall determines the thoracic aortic size and abnormalities in aortic functional indices. BMI and age were also independent predictors of thoracic aortic dilatation. Keywords: Obstructive sleep apnea, hypertension, aortic root dilatation, acute myocardial infarction (Source: Sleep)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Obstructive Sleep Apnea and Aging Effects on Macrovascular and Microcirculatory Function
Conclusions: In obesity, both OSA and aging impair endothelial function and increase arterial stiffness. The influence of OSA on vascular function is most pronounced in young subjects. OSA, therefore, may be associated with functional impairment (&ldquo;a premature aging effect&rdquo;) on the endothelium and on arterial stiffness (in men), although skin microcirculatory function appears preserved. Keywords: Sleep, lung, breathing, vascular, apnea, airway, hypoxemia (Source: Sleep)
Catecholamines, Adiponectin, and Insulin Resistance as Measured by HOMA in Children with Obstructive Sleep Apnea
Conclusions: In obese pubertal children, OSA was associated with worse insulin resistance. Worsening OSA was associated with lower adiponectin and increasing urinary catecholamines. Whether OSA directly lowers adiponectin and aggravates a predisposition to insulin resistance is unknown, but these preliminary findings highlight the importance of further studying pediatric OSA. Keywords: Obstructive sleep apnea, insulin resistance, adiponectin, pediatrics (Source: Sleep)
Consequences of Comorbid Sleep Apnea in the Metabolic Syndrome&mdash;Implications for Cardiovascular Risk
Conclusion: Patients with MetSyn and comorbid OSA have higher BP, higher sympathetic drive, and diminished BRS, compared with patients with MetSyn without OSA. These adverse cardiovascular and autonomic consequences of OSA may be associated with poorer outcomes in these patients. Moreover, increased BP and sympathetic drive in patients with MetSyn+OSA may be linked, in part, to impairment of baroreflex gain. Keywords: Cardiovascular risk, sleep apnea, metabolic syndrome, sympathetic activation, baroreflex control (Source: Sleep)
The Association of Sleep Duration with Adolescents&rsquo; Fat and Carbohydrate Consumption
Conclusion: Quantitative measures of macronutrient intake in adolescents were associated with objectively measured sleep duration. Short sleep duration may increase obesity risk by causing small changes in eating patterns that cumulatively alter energy balance. Keywords: Sleep duration, diet, obesity, adolescents, 24-hour food recall (Source: Sleep)
Insomnia Symptoms and Daytime Function in Stable Heart Failure
Conclusions: Insomnia symptoms are common in patients with stable heart failure and are associated with daytime symptoms and decrements in functional performance. Keywords: Depression, fatigue, heart failure, insomnia, quality of life, sleep (Source: Sleep)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Enhancing Slow Wave Sleep with Sodium Oxybate Reduces the Behavioral and Physiological Impact of Sleep Loss
Conclusions: Pharmacological enhancement of SWS with sodium oxybate resulted in a reduced response to sleep loss on measures of alertness and attention. In addition, SWS enhancement during sleep restriction appears to result in a reduced homeostatic response to sleep loss. Keywords: Slow wave sleep, sleepiness, attention, sleep deprivation, sodium oxybate (Source: Sleep)
Energy Expenditure is Affected by Rate of Accumulation of Sleep Deficit in Rats
Conclusion: The change in VdotO2 is affected by rate of accumulation of sleep deficit and not the total sleep loss accrued. Negative energy balance, observed during TSD, is strongly attenuated when brief daily sleep opportunities are available to rats (CSR), despite greater accumulated sleep deficit. Keywords: Body temperature, chronic sleep restriction, core sleep, energy balance, energy metabolism, oxygen uptake, sleep debt, total sleep deprivation (Source: Sleep)
The Injection of Hypocretin-1 into the Nucleus Pontis Oralis Induces either Active Sleep or Wakefulness Depending on the Behavioral State when it is Administered
Conclusions: The present data demonstrate that the behavioral state of the animal dictates whether active sleep or wakefulness is induced following the injection of hypocretin. Therefore, we suggest that hypocretin-1 enhances ongoing states of wakefulness and their accompanying patterns of physiologic activity and that hypocretin-1 is also capable of promoting active sleep and the changes in various processes that occur during this state. Keywords: Microinjection, orexin, wakefulness, REM sleep, nucleus pontis oralis (Source: Sleep)
Increased Disease Activity is Associated with Altered Sleep Architecture in an Experimental Model of Systemic Lupus Erythematosus
Conclusions: The sleep-recording data showed that, during the progress and severe phases of the disease (19 and 29 wks of age, respectively), sleep architecture is altered. According to these results, increased sleep fragmentation, disease activity, and pain sensitivity are features observed in these mice, similar to symptoms of SLE. Keywords: Antinuclear antibody, lupus, (NZB/NZW)F1 mice, pain, sleep recording (Source: Sleep)
Relationship Between Surface Facial Dimensions and Upper Airway Structures in Obstructive Sleep Apnea
Conclusions: This study demonstrates that there is a relationship between surface facial dimensions and upper airway structures in subjects with OSA. These findings support the potential role of surface facial measurements in anatomic phenotyping for OSA. Keywords: Obstructive sleep apnea, facial phenotype, upper airway structures, magnetic resonance imaging (Source: Sleep)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Assessing the Prioritization of Primary Care Referrals for Polysomnograms
Conclusion: In a public hospital, primary care patients were less likely to be referred for PSG compared to mammogram and endoscopy. Uninsured patients were more likely to be referred for PSG than those with private insurance. Further studies are needed to address the low PSG referral rates in high-risk populations. Keywords: Sleep apnea, primary care, referral, health care delivery, socioeconomic status (Source: Sleep)
Narcolepsy: A Clinical Guide
Edited by Goswami, M., Pandi-Perumal, S. R., Thorpy, M. J.; Humana Press, Springer, New York; 330 pages; $219.00 (Source: Sleep)
How insomnia 'can send men to an early grave' - But are women immune to the dangers?
According to a study, male insomniacs are far more likely to die prematurely than those who regularly get a good night's sleep. (Source: the Mail online | Health)
Contribution of adenosine related genes to the risk of depression with disturbed sleep
Abstract: Background: Most patients with major depression report problems in their sleep: insomnia, early morning awakenings and fatigue correlating with poor sleep quality. One of the key substances regulating sleep is adenosine. We hypothesized that variations in polymorphic sites of adenosine related genes may predispose to depression with sleep disturbances.Methods: We selected 117 single nucleotide polymorphisms from 13 genes and analyzed their association with depression and specific sleep problems (early morning awakenings and fatigue). Data were collected as part of the Health 2000 Study based on Finnish population and included 1423 adult subjects.Results: Our major finding herein was, among women, the association of SLC29A3 polymorphism rs12256138 with depressive disorder (p=0.000...
Symptoms and signs of the initial prodrome of bipolar disorder: A systematic review
Conclusions: The initial prodrome of BD is characterized by dysregulation of mood and energy. Because of the apparently low specificity of prodromal symptoms and signs of BD, it is currently neither possible nor advisable to predict the development of BD based solely on early phenomenology. More well-designed in-depth studies, including qualitative ones, are needed to characterize the initial bipolar prodrome. (Source: Journal of Affective Disorders)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Teens: Sleep Less, Eat More
(Ivanhoe Newswire) -- Here's one more reason to make sure your child is getting enough rest: Teenagers who don't get enough sleep eat more fatty foods and snacks. (Source: Medical Headlines From Ivanhoe.com)
Study links shorter sleep durations with greater risks of mental distress in young adults
(American Academy of Sleep Medicine) Results show a linear association between sleep durations of less than eight hours and psychological distress in young adults between 17 and 24 years of age. The risk of psychological distress increased by 14 percent for each hour of nightly sleep loss. Those sleeping less than six hours a night were twice as likely to be experiencing distress as average sleepers. Long sleep durations of more than nine hours showed no association with distress. (Source: EurekAlert! - Medicine and Health)
Study finds an increased risk of death in men with insomnia and a short sleep duration
(American Academy of Sleep Medicine) Men with chronic insomnia who slept for less than six hours were four times more likely to die during the 14-year follow-up period. Results were adjusted for potential confounders such as body mass index, smoking status, depression and obstructive sleep apnea. Further adjustments for hypertension and diabetes had little effect on the elevated mortality risk. No significant mortality risk was found in women with insomnia and a short sleep duration of less than six hours. (Source: EurekAlert! - Medicine and Health)
Less is more: Study shows that teens who sleep less eat more fatty foods and snacks
(American Academy of Sleep Medicine) Teens who slept less than eight hours on weeknights consumed 2.2 percent more calories from fats and 3 percent fewer calories from carbs than teens who slept eight hours or more. In secondary analyses stratified by sex, the results were significant among girls but not boys. Also, for each one-hour increase in sleep duration, the odds of consuming a high amount of calories from snacks decreased by an average of 21 percent. (Source: EurekAlert! - Medicine and Health)
New Moms Get Enough Sleep, Just Not Good Sleep
Contrary to popular belief, new mothers may often get a decent amount of sleep in their babies' first few months -- but it's not a good-quality sleep, a new study suggests. Reuters Health Information (Source: Medscape ObGyn and Womens Health Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Problems with combining esophagogastroduodenoscopy and colonoscopy to analyze risks of transient hypoxia from procedures in patients with risk factors for obstructive sleep apnea: a call for stratifying risks according to individual procedures
Obstructive sleep apnea is increasingly being diagnosed, and its cardiopulmonary risks are being increasingly elucidated, but the risks of GI endoscopy in patients with obstructive sleep apnea is previously unstudied. Thus the article by Khiani et al related to this subject is particularly welcomed and important. Khiani et al show no significant difference in the rates of transient hypoxia between relatively high-risk and relatively low-risk groups for obstructive sleep apnea. I have 2 comments about this article. First, the authors analyze patients at relatively high risk of obstructive sleep apnea but exclude patients with diagnosed obstructive sleep apnea and 2 other significant cardiopulmonary conditions, chronic obstructive pulmonary disease and congestive heart failure. Thus, their c...
Response
We greatly appreciate Dr Cappell's insights and discussion of the strengths and weaknesses of our study. Obstructive sleep apnea is a condition that deserves attention in patients undergoing endoscopy. In particular, there are an increasing number of patients with undiagnosed obstructive sleep apnea who are undergoing endoscopy. While Dr Cappell is correct in stating that the overall prevalence of diagnosed obstructive sleep apnea may be around 3% to 7%, it has been estimated that the overall prevalence of obstructive sleep apnea in the U.S. population is approximately 20% with approximately 90% of all obstructive sleep apnea being undiagnosed. This is an under-recognized disease. Because there is a lack of literature on the percentage of patients at high risk for obstructive sleep apnea w...
The attitudes to CPAP treatment inventory: development and initial validation of a new tool for measuring attitudes to CPAP treatment
(Source: Journal of Sleep Research)
Insomnia, Short Sleep Duration Linked to Mortality in Men
Insomnia with objective short sleep duration is related to an increased risk of mortality among men, according to research published in the Sept. 1 issue of SLEEP. (Source: Modern Medicine)
Small-Gauge Pars Plana Vitrectomy: A Report by the American Academy of Ophthalmology
Conclusions: The technological advances of small-gauge vitrectomy seem to afford visual benefit comparable with that seen with traditional 20-gauge surgery, with more rapid healing, less discomfort, and an acceptably low incidence of adverse events comparable with those observed with conventional 20-gauge vitrectomy. As surgical techniques evolve and clinical experience grows, continued close surveillance is necessary for an accurate assessment of complications.Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (Source: Ophthalmology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Ranibizumab and Stroke
We would like to thank Boyer et al. for addressing the safety issues in patients with neovascular age-related macular degeneration (AMD) on intravitreal ranibizumab. In their study, a total of 4300 subjects were enrolled in 2 cohorts. Cohort 1 subjects were randomized 1:1 as follows: those who received 0.3 mg ranibizumab/shot with 3 monthly loading doses and then as needed thereafter; and those who were on the same regimen but received 0.5 mg ranibizumab/shot. Cohort 2 subjects received 0.5 mg ranibizumab/shot without loading doses. The study did not have a control group in which ranibizumab was not used. The subjects were not as intensively treated as those in previous pivotal clinical studies, as cohort 1 and 2 subjects received an average of 4.6 and 3.6 shots during the 12-month study p...
Sleep Research Society Young Investigator Award
The deadline to submit nominations for all SRS Awards is Friday, September 17, 2010. Nominations may be sent via e-mail to ncekosh@srsnet.org or they can be mailed to the Sleep Research Society, Attn: Nick Cekosh, 2510 North Frontage Road, Darien, IL 60561. This award recognizes an outstanding research effort by a new investigator in the field of sleep research. The basis for evaluation of candidates is a single publication in a refereed journal. The candidate should be the first author; and the article must be published or officially accepted for publication by the application deadline. On the application deadline, the candidate must be within 7 years of obtaining a terminal degree. Exceptions to this criterion will be considered for those applicants who feel that extenuating circ...
Hungry flies ok with less sleep
There may be certain conditions under which animals can forgo sleep without serious consequences (Source: The Scientist)
Lack of effects on lymphocyte function from chronic topical ocular cyclosporine medication: a prospective study
Abstract (Source: Veterinary Ophthalmology)
The central motor conductivity of genioglossus in obstructive sleep apnea
(Source: Respirology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Reevaluating Obstructive Sleep Apnea as a Risk Factor for Cerebrovascular Disease
Over the past quarter century, multiple studies have firmly established an association between obstructive sleep apnea syndrome (OSAS) and stroke. Case reports, case series, and case-control studies have demonstrated an ?70% prevalence of OSAS in stroke survivors. Furthermore, the severity of OSAS (Apnea Hypopnea Index [AHI] of >30/hour) is much higher in stroke patients than in controls. In many cases, the symptoms of OSAS precede the occurrence of stroke, suggesting a cause-and-effect relationship. (Source: Journal of Stroke and Cerebrovascular Diseases)
CASE STUDY: Diagnostic challenge: Myasthenia gravis in the emergency department
Abstract (Source: Journal of the American Academy of Nurse Practitioners)
Ocular leech infestation.
Authors: Dey R, Dey S A 67-year-old myopic man presented to the Ophthalmology Department of a teaching hospital in the mountainous state of Sikkim with complaints of red eye, ocular discomfort, and sensation of something moving in his right eye that lead to occasional visual blurring from the previous four days. His symptoms started after washing his face in a stream. Clinical diagnosis was a leech in the limbus of the right eye at the 12 o'clock position. Ocular leech infestation should be considered in a patient with a history of swimming or face washing in streams and lakes. Herein we report a case of ocular leech infestation that presented as red eye with intermittent blurring of vision in the affected eye, and discuss the differential diagnosis and clinical significance. PMID:...
Progression of low back and lower extremity pain in a cohort of patients with achondroplasia.
Conclusions Individuals with achondroplasia and symptomatic spinal stenosis often experience back pain, which may progress to lower extremity pain and debilitating consequences. A more thorough understanding of the progression of spatial pain characteristics and pain severity may aid clinical decision making regarding the optimal timing for intervention. PMID: 20809726 [PubMed - in process] (Source: Journal of Neurosurgery.Spine)
Maxillary, mandibular and chin advancement surgery for the treatment of obstructive sleep apnoea
Abstract (Source: Australian Dental Journal)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Hypoxia-Inducible Factor-1 in Arterial Disease: A Putative Therapeutic Target.
Authors: Kasivisvanathan V, Shalhoub J, Lim CS, Shepherd AC, Thapar A, Davies AH Hypoxia-inducible factor-1 (HIF-1) is a nuclear transcription factor that is upregulated in hypoxia and co-ordinates the adaptive response to hypoxia by driving the expression of over 100 genes. In facilitating tissues to adapt to hypoxia, HIF-1 may have a role in reducing the cellular damage induced by ischaemia, such as that seen in peripheral arterial disease (PAD), or following acute ischaemic insults such as stroke and myocardial infarction. This therefore raises the possibility of HIF-1 modulation in such contexts to reduce the consequences of ischaemic injury. HIF1 has further been implicated in the pathogenesis of atherosclerosis, abdominal aortic aneurysm (AAA) formation, pulmonary hypertension an...
Sleep deprivation suppresses the increase of rapid eye movement density across sleep cycles
(Source: Journal of Sleep Research)
Continucare acquires sleep diagnostic centers
Continucare Corp. said its subsidiary acquired an operator of two sleep diagnostic centers in South Florida. (Source: bizjournals.com Health Care:Health Insurance headlines)
Continucare acquires sleep diagnostic centers
Continucare Corp. said its subsidiary acquired an operator of two sleep diagnostic centers in South Florida. (Source: bizjournals.com Health Care:Biotechnology headlines)
LEDs Illuminate Eye for Ocular Disease Screening
August 31, 2010 (EurekAlert)  - A new imaging system using six different wavelengths to illuminate the interior of the eyeball (ocular fundus) may pave the way for doctors to easily screen patients for common diseases of the eye, such as age-related macular degeneration and diabetic retinopathy. The system is described in the journal Review of Scientific Instruments, which is published by the American Institute of Physics. read more (Source: Diabetes News from dLife.com)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
An Overview of the Treatment of Tourette's Disorder and Tics
Journal of Child and Adolescent Psychopharmacology Aug 2010, Vol. 20, No. 4: 249-262. (Source: Journal of Child and Adolescent Psychopharmacology)
Association Between Antipsychotics and Body Mass Index When Treating Patients with Tics
Journal of Child and Adolescent Psychopharmacology Aug 2010, Vol. 20, No. 4: 277-281. (Source: Journal of Child and Adolescent Psychopharmacology)
What Are Bedbugs? Are They Dangerous? [Repost]
This article originally appeared on February 27, 2009. We are reposting it because of current concern about bedbugs. NEW YORK--Sleep tight and don't let the bedbugs bite? If only . The creepy critters have become such a nuisance here that the city council is mulling legislation that would establish a bedbug task force, ban the sale of used mattresses, train exterminators, and regulate mattress disposal. Just how infested is Gotham? According to the New York Daily News , there were 22,218 complaints to the city's 311 hotline about infestations of the blood-sucking hemipterans, a 34 percent jump since this time last year. [More] (Source: Scientific American - Official RSS Feed)
What Are Bedbugs? Are They Dangerous? [Re-post]
This article originally appeared on February 27, 2009. We are re-posting it because of current concern about bedbugs. NEW YORK--Sleep tight and don't let the bedbugs bite? If only . The creepy critters have become such a nuisance here that the city council is mulling legislation that would establish a bedbug task force, ban the sale of used mattresses, train exterminators, and regulate mattress disposal. Just how infested is Gotham? According to the New York Daily News , there were 22,218 complaints to the city's 311 hotline about infestations of the blood-sucking hemipterans, a 34 percent jump since this time last year. [More] (Source: Scientific American - Official RSS Feed)
The Neural Basis of the Depressive Self
Depression is actually defined by specific clinical symptoms such as sadness, difficulty to experience pleasure, sleep problems etc., present for at least two weeks, with impairment of psychosocial functioning. (Source: Disabled World)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
In depression, it's the physical symptoms that carry heart risk
The loss of interest, ruminations of suicide and feelings of guilt and sadness that are the hallmarks of depression may be debilitating. But it is depression's physical warning signs -- fatigue, sleep disturbance and appetite changes -- that are the... (Source: OrlandoSentinel: Medical Research)
Can Parents Help College Students Too Much?
As school starts this week in our part of the country, three images of adolescence are banging together in my brain.First are the kids - bleery with sleep and looking like great, landlocked turtles - meandering down the sidewalks of our small town towards their first days in middle school.&nbsp;Second are the late adolescents - early adults - arriving with suitcases, boxes, and parents in tow to begin their college careers.&nbsp; Orientation begins in just over an hour, and the little diners in town have been crowded with families since early morning.Third are the incredibly mature - and sometimes wildly adolescent - young men and women I see on my video screen, interviewed about their experiences in Iraq, getting ready to listen to the President talking about how the first part of their l...
The neural basis of the depression
Depression is actually defined by specific clinical symptoms such as sadness, difficulty to experience pleasure, sleep problems etc., present for at least two weeks, with impairment of psychosocial functioning. These symptoms guide the doctor to make a diagnosis and to select antidepressant therapy such as drugs or psychotherapy........ (Source: Medicineworld.org: New Article Alert)
Defining Depression At The Neurobiological Level
Depression is actually defined by specific clinical symptoms such as sadness, difficulty to experience pleasure, sleep problems etc., present for at least two weeks, with impairment of psychosocial functioning. These symptoms guide the physician to make a diagnosis and to select antidepressant treatment such as drugs or psychotherapy. At least 40% of depressed patients actually benefit from antidepressant treatment, whereas 20-30% of patients may suffer from chronic depression that negatively impacts their quality of life... (Source: Health News from Medical News Today)

of people out there and brushing off your sleep and energy problems and becoming addicted to that cup of joe in the morning, properly assessing the situation and attacking the problem at its roots will cure you of your global insomnia.

How do I know if I have global insomnia?

While it seems strange that someone could have this condition and not know it, the mind can be relaxed enough to stay asleep while the body moves and is not resting. This is the primary cause of the lack of energy experienced by insomniacs.

The more obvious ways to tell are things like taking more than 30 minutes to fall asleep every night, frequently waking up throughout the night or waking up too early and not being able to fall back asleep. Mind you, all of these happen to everyone, but if they happen to you on a regular basis, there is a good chance something could be done to treat them.

So, rather than deal with your low energy levels, body aches, memory loss, lack of attention to detail and motivation, determine if you have global insomnia so the problems can be eliminated. If you aren't able to tell, see your doctor for a sleep test.

Once you have determined that you have a case of global insomnia, you can use many techniques to cure you of its symptoms. To feel more energized and focused throughout the day, try waning off of caffeine and refined sugar, and drinking water every hour. Also, be sure to eat properly and exercise regularly to wear your body out and build stamina at the same time.

There are many other methods to regain your energy including soothing music, changing your sleeping environment and even prescriptions. With a combination of these methods, you will get your youthful energy back again, and actually enjoy waking up to your alarm clock!



We strive to provide only quality articles, so if there is a specific topic related to sleep disorders that you would like us to cover, please contact us at any time.

SLEEP IS A TERRIBLE THING TO WASTE!

Notes from Chicago
I am Lily, a new postdoc at Argonne National Lab. I'm the one who thinks she can find the Higgs boson by listening to it. Thanks Jon for letting me play on your blogIt's a walk in the parkI moved here just over a week ago to work on Atlas physics analysis (Atlas is one of the detectors at the LHC). So far the closest I have got to doing any physics here is talking about ways to limit the shock a colleague gets from the carpet-humidity-doorknob setup in his office here. But that's a start.Argonne have excellent childcare facilitiesI'm loving it here so far. It was a tricky one deciding whether to move 4000 miles from London with an 11-year-old child and no driving license. I'm glad we did.Argonne is full of smart people doing interesting physics. My PhD was on the search for the Higgs boso...
Depression Significantly Improved By Non-Invasive Therapy
Major depression is a common and disabling brain condition marked not only by the presence of depressed mood but also by its effects on sleep, energy, decision-making, memory and thoughts of death or of suicide. Major depression affects 15 million adults in the U.S., and the World Health Organization projects that by 2020, it will be the largest contributor to disability in the world after heart disease. While antidepressants have helped many to recover and resume their lives, only 30 percent of patients will experience full remission with the first medication they use... (Source: Health News from Medical News Today)
Owl Monkeys Need Moonlight As Much As A Biological Clock For Nocturnal Activity
An international collaboration led by a University of Pennsylvania anthropologist has shown that environmental factors, like temperature and light, play as much of a role in the activity of traditionally nocturnal monkeys as the circadian rhythm that regulates periods of sleep and wakefulness. The study also indicates that when the senses relay information on these environmental factors, it can influence daily activity and, in the case of a particular monkey species, may have even produced evolutionary change... (Source: Health News from Medical News Today)
Starvation keeps sleep-deprived fly brain sharp
As anyone who has ever struggled to keep his or her eyes open after a big meal knows, eating can induce sleepiness. New research in fruit flies suggests that, conversely, being hungry may provide a way to stay awake without feeling groggy or mentally challenged. (Source: ScienceDaily Headlines)
Male insomniacs at increased risk of death
Men who suffer from insomnia and who sleep for under six hours a night have an increased risk of dying, according to a US study. (Source: Nursing Times Breaking News)
Rough transition into menopause
Perimenopausal symptoms can go beyond hot flashes and may include sleep problems, psychological distress and mental lapses. Treatment options are limited, but research is ongoing.I'm 46, and there are days when it feels like I'm completely losing my mind. I misplace my car keys, struggle to remember details of recent conversations, and can't recall seemingly anybody's name. To help cope with my mental cloudiness, I always keep an extra set of keys nearby, write endless sticky notes to myself, and frequently opt for the generic "hello" over more personalized greetings. (Source: L.A. Times - Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
FDA Approves New Eye Pressure Drop Formulation
WASHINGTON (MedPage Today) -- The FDA approved a new formulation of the drug bimatoprost (Lumigan) in a 0.01% solution as a first-line treatment to reduce elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. (Source: MedPage Today Public Health)
Disturbances of the Mind
by Douwe Draaisma is a book regarding various illnesses ranging from Bonnet Syndrome to Alzheimer?s, with an entire range of brain diseases in between.  It provides an interesting narrative about how each disease came to be identified, by whom, the disease&#8217;s symptoms, and how it came to be named.  This book provides a historical background on these diseases and would be particularly useful for persons interested in the medical field.  It may also provide some insights on the disease for people with family members or friends who may unfortunately be afflicted.  This book, while interesting, is not deemed a page-turner initially.  However, it continues to pique the reader?s interest and even becomes quite fascinating in the latter chapters.  While each disease is covered in ...
Audio » John Piacentini on Treating Tics Associated With Tourette Syndrome
Dr. John Piacentini of UCLA talks about CBIT, a new therapy that treats tics associated with Tourette's Syndrome (Source: National Institute of Mental Health)
Marijuana better than pharmaceuticals at treating chronic pain, improving mood
(NaturalNews) Experts from different persuasions often argue about the alleged benefits of using marijuana for pain relief, but a new study out of McGill University Health Centre (MUHC) and McGill University (MU) has conclusively found that cannabis, the genus name for marijuana, is better than pharmaceutical drugs at relieving chronic neurological pain, and without all the harmful side effects.Appearing in the latest issue of the Canadian Medical Association Journal, the study reveals that tetrahydrocannabinol (THC), the active ingredient in marijuana that gives it psychoactive and analgesic properties, is linked to relieving chronic pain, improving mood and inducing better sleep in those with severe neurological pain. Patients who took a single inhalation of marijuana smoke three times a...
Treatment Options for Parasomnias
Parasomnias are undesirable physical or experiential events that occur in and around sleep. Treatments include reassurance in some cases, various forms of cognitive-behavioral therapy (CBT), and pharmacologic agents. Cognitive restructuring, imagery rehearsal, relaxation, hypnosis, desensitization, and anticipatory awakenings are some of the common CBT and nonpharmacologic interventions. Medications that are used belong to a wide variety of pharmacologic classes, such as ?-blockers (prazosin), tricyclic antidepressants (imipramine and clomipramine), selective serotonin reuptake inhibitors, benzodiazepines (diazepam and clonazepam), anticonvulsants (topiramate and gabapentin), desmopressin acetate, and anticholinergic agents (oxybutynin and tolterodine). Data on efficacy are only available...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Guidelines for insomnia, sleep disorders
LONDON, Sept. 4 (UPI) -- The British Association for Psychopharmacology has created guidelines to help psychiatrists and physicians treat those with sleep problems, researchers say. Sleep disorder - Insomnia - Health - Conditions and Diseases - United States (Source: Health News - UPI.com)
Guidelines for sleep problems offered
LONDON, Sept. 4 (UPI) -- The British Association for Psychopharmacology has created guidelines to help psychiatrists and physicians treat those with sleep problems, researchers say. Sleep disorder - Health - Conditions and Diseases - Psychiatrist - United States (Source: Health News - UPI.com)
Predicting Obstructive Sleep Apnea Among Women Candidates for Bariatric Surgery
Journal of Women's Health , Vol. 0, No. 0. (Source: Journal of Women)
FDA Approves Bimatoprost 0.01% Eye Drops For Elevated Intraocular Pressure
FDA has approved bimatoprost 0.01% ophthalmic solution for the first-line treatment of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Medscape Medical News (Source: Medscape Pharmacist Headlines)
Life with Infertility is Hectic!
Whether your infertility is newly diagnosed or a condition for which you've received long term treatment, "hectic" is likely to be a familiar word in your vocabulary. However, for you, the frustrating aspect of "hectic" is that it is punctuated by periods of waiting -- for test results, for procedures, for consultations, and -- of course-- for a pregnancy. In my book When You're Not Expecting, I refer to this as the period when your life is on hold.So, what's to do when you feel as if you're dancing to the tune of your infertility specialist, clinic schedules and medical procedures? Undoubtedly you will search for ways to lift your spirits, distract yourself from disappointing news, consider new options and nurture your relationships. These are all components of emotional resilience, a fam...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Insomnia Means More Than A Bad Night's Sleep
A new study says men who reported having insomnia and who slept less than 6 hours a night were four times more likely to die over a 14-year period when compared to men who reported sleeping well. Sleep researcher and psychiatrist Alexandros Vgontzas explains the finding.&raquo; E-Mail This&nbsp;&nbsp;&nbsp;&nbsp; &raquo; Add to Del.icio.us (Source: NPR Health and Science)
Mammalian Telomeric DNA Suppresses Endotoxin-induced Uveitis [Dna and Chromosomes]
This study demonstrates the selective down-regulatory role of suppressive ODN after (i) local or (ii) systemic treatment in EIU-induced rabbits and mice. Our results indicate that suppressive ODN down-regulate at both the transcript and protein levels of several proinflammatory cytokines and chemokines as well as nitric oxide and co-stimulatory surface marker molecules when administrated prior to, simultaneously with, or even after LPS challenge, thereby significantly reducing ocular inflammation in both rabbit and mouse eyes. These findings strongly suggest that suppressive ODN is a potent candidate for the prevention of uveitis and could be applied as a novel DNA-based immunoregulatory agent to control other autoimmune or autoinflammatory diseases. (Source: Journal of Biological Chemistr...
New guidelines to ease sleepless nights
Insomnia and other sleep disorders are very common, yet are not generally well understood by doctors and other health care professionals. Now the British Association for Psychopharmacology (BAP) has published new guidelines to guide psychiatrists and physicians caring for those with sleep problems. The research, led by Dr Sue Wilson, Senior Research Fellow in Psychopharmacology at the University of Bristol, provides a comprehensive guide on the best current treatments for sleep disorders to clinicians, who are managing patients in primary or secondary medical care. (Source: University of Bristol news)
A Review of the Surgical Treatment Options for the Obstructive Sleep Apnea/Hypopnea Syndrome Patient
(Source: Military Medicine)
Easing Sleepless Nights: New Guidelines
Insomnia and other sleep disorders are very common, yet are not generally well understood by doctors and other health care professionals. Now the British Association for Psychopharmacology (BAP) has released up-to-the-minute guidelines in the Journal of Psychopharmacology, published by SAGE, to guide psychiatrists and physicians caring for those with sleep problems... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Pivotal Study Finds Link Between PTSD And Dementia
Results of a study reported in the September issue of the Journal of the American Geriatrics Society suggest that Veterans with post-traumatic stress disorder (PTSD) have a greater risk for dementia than Veterans without PTSD, even those who suffered traumatic injuries during combat. Exposure to life threatening events, like war, can cause PTSD, and there are high rates among veterans. PSTD includes symptoms such as avoiding things or people that remind a person of the trauma, nightmares, difficulty with sleep, and mood problems... (Source: Health News from Medical News Today)
Teens Who Sleep Less Eat More Fatty Foods And Snacks
A study in the Sept. 1 issue of the journal Sleep shows that teens who slept less than eight hours per weeknight ate higher proportions of fatty foods and snacks than adolescents who slept eight hours or more. The results suggest that short sleep duration may increase obesity risk by causing small changes in eating patterns that cumulatively alter energy balance, especially in girls... (Source: Health News from Medical News Today)
Moonstruck primates: Owl monkeys need moonlight as much as a biological clock for nocturnal activity
(University of Pennsylvania) An international collaboration led by a University of Pennsylvania anthropologist has shown that environmental factors, like temperature and light, play as much of a role in the activity of traditionally nocturnal monkeys as the circadian rhythm that regulates periods of sleep and wakefulness. (Source: EurekAlert! - Biology)
Sleep lack, mental stress in ages 17-24
SYDNEY, Sept. 2 (UPI) -- Researchers in Australia say they have found a link between shorter sleep times and higher risk of mental distress in young adults. Health - Stress - Conditions and Diseases - Sleep Disorders - Research (Source: Health News - UPI.com)
Men With Insomnia May Have Higher Risk of Death
Men with insomnia have a fourfold higher death rate than those who sleep at least 6 hours a night, a 14-year study finds. It's not yet clear whether women with insomnia also die sooner. (Source: WebMD Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Insomnia and its correlates in a representative sample of the Greek population
Conclusions: The present study confirms most findings reported from other developed countries around the world regarding the high prevalence of insomnia problems in the general population and their association with several sociodemographic and health-related predisposing factors. These results further indicate the need for more active interventions on the part of physicians who should suspect and specifically ask about such symptoms. (Source: BMC Public Health - Latest articles)
Quantification of vestibular-induced eye movements in zebrafish larvae
Conclusions: Our results provide evidence for a functional vestibulo-oculomotor circuit in 72 hpf zebrafish larvae that relies upon sensory input from anterior/utricular otolith organs. (Source: BioMed Central)
Human ocular carotenoid-binding proteins
Binxing Li, Preejith Vachali, Paul S. Bernstein (Perspective from Photochem. Photobiol. Sci.) Binxing Li, Photochem. Photobiol. Sci., 2010, DOI: 10.1039/c0pp00126k To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Photochem. Photobiol. Sci. latest articles)
Circadian Rhythms and Body Cycles
Circadian Rhythms: Their role and dysfunction in affective disorder. (Source: Disabled World)
Non-invasive therapy significantly improves depression, UCLA researchers say
Major depression is a common and disabling brain condition marked not only by the presence of depressed mood but also by its effects on sleep, energy, decision-making, memory and thoughts of death or of suicide. &nbsp; Major depression&nbsp;affects 15 million adults in the U.S., and the World Health Organization projects that by 2020, it&nbsp;will be the largest contributor to disability in the world after heart disease. &nbsp; While antidepressants have helped many to recover and resume their lives, only 30 percent of patients will experience full remission with the first medication they use. Patients typically move on to try a series of other antidepressants. A persistent problem with such drugs has been major side effects, including obesity, sexual dysfunction, fatigue, drowsiness and n...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
For teens, too little sleep may equal too many snacks
All those late nights spent trolling Facebook, texting friends, and cramming for tests may be taking a toll on teenagers' diets, a new study suggests. (Source: CNN.com - Health)
How to Get to Sleep on Sleepless Nights - New Guidelines
New guidelines to ease sleepless nights - Insomnia and other sleep disorders are very common, yet are not generally well understood by doctors and other health care professionals. (Source: Disabled World)
Short Sleep And Chronic Insomnia Linked To Four-Fold Risk Of Early Death In Men
US researchers found that short sleep and insomnia was linked to a four times higher risk of early death in men; they urged public health policy makers to emphasize earlier diagnosis and treament of chronic insomnia. You can read how researchers from the Pennsylvania State University College of Medicine, in Hershey, Pennsylvania, came to these findings in a paper they wrote that was published on 1 September in the journal SLEEP... (Source: Health News from Medical News Today)
Drug-induced sleep endoscopy: conventional versus target controlled infusion techniques?a randomized controlled study
Abstract&nbsp;&nbsp;Understanding the sites of pharyngeal collapse is mandatory for surgical treatment decision-making in obstructive sleep-apnea-hypopnea syndrome patients. Drug-induced sleep endoscopy (DISE) allows for the direct observation of the upper airway during sedative-induced sleep. In order to re-create snoring and apnea patterns related to a spontaneous sleep situation, the authors used a target-controlled infusion (TCI) sleep endoscopy (DISE-TCI), comparing this technique to conventional DISE, in which sedation was reached by a manual bolus injection. The authors conducted a prospective, randomized, unicenter study. The apneic event observation and its correlation with pharyngeal collapse patterns is the primary endpoint; secondary endpoints are defined as stability and ...
Too little sleep bad for teenagers' diets: study
CHICAGO (Reuters) - Teenagers who sleep less than eight hours a night on weeknights eat more fatty foods and snacks than those who get more than eight hours of sleep a night, U.S. researchers said on Wednesday. (Source: Reuters: Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Cannabis for nerve pain studied
?Smoking cannabis from a pipe can significantly reduce chronic pain in patients with damaged nerves,? reported the BBC. It added that improvements in sleep and anxiety were seen. (Source: Neurological Conditions Specialist Library)
Better Than Coffee
Dear Health Conscious Reader, People love this stuff, so in case you missed this? I have something that will electrify you? It?s even better than coffee. When I was hiking through the Amazon Rain Forest last year, I had a first-hand experience with a remarkable healing herb. This rain forest herb gives you lasting energy ? without the crash. Sacred to the nearby Guarani tribe, it was literally a gift  the gods. According to tribal folklore, the Indians of the Amazon River Basin have been using it to prevent fatigue and increase physical endurance since before recorded history. I took it in the early morning before we hit the trail. After 18 hours through the jungles of Peru my mind was crystal clear and I had no feeling of fatigue. Looking back, I had covered 15 miles of rugged te...
A novel method of culturing human oral mucosal epithelial cell sheet using post-mitotic human dermal fibroblast feeder cells and modified keratinocyte culture medium for ocular surface reconstruction
Conclusion This novel culture method using dermal fibroblasts and pharmaceutical agents provides a safe cell processing system without xenogenic feeder cells for ocular surface reconstruction. (Source: British Journal of Ophthalmology)
The prevalence and causes of visual impairment in indigenous Australians within central Australia: the Central Australian Ocular Health Study
Conclusion This study indicates that bilateral visual impairment and blindness are, respectively, 25.1% and 3.6% among indigenous Australians, four to seven times higher than among the non-indigenous Australian population. Trachoma is the leading cause of bilateral blindness after refractive error and cataract. (Source: British Journal of Ophthalmology)
Long-term ocular complications in aphakic versus pseudophakic eyes of children with juvenile idiopathic arthritis-associated uveitis
Conclusion With maximum control of perioperative inflammation and intensive follow-up, the implantation of an intraocular lens in well-selected eyes of children with JIA-associated uveitis is not associated with an increased risk of ocular hypertension, secondary glaucoma, cystoid macular oedema and optic disc swelling and showed better visual results up to and including 7&nbsp;years after cataract extraction. (Source: British Journal of Ophthalmology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Sampling and measurement methods for a study of childhood refractive error in a UK population
Conclusions The study design, sample size and methodology will ensure accurate measures of the prevalence of refractive errors in the target population and will facilitate comparisons with other population-based refractive data. (Source: British Journal of Ophthalmology)
Eye movement recordings to investigate a supranuclear component in chronic progressive external ophthalmoplegia: a cross-sectional study
Conclusions This study does not support a supranuclear component to the ophthalmoplegia of CPEO, although the increased latencies observed may warrant further investigation. (Source: British Journal of Ophthalmology)
Delayed adjustable sutures: a multicentred clinical review
Conclusions This large multicentred series characterises the closed conjunctival delayed adjustable suture technique for the correction of strabismus. It may present some significant advantages to more traditional adjustable suture techniques. (Source: British Journal of Ophthalmology)
New Guidelines Issued for Insomnia and Other Sleep Disorders
The British Association for Psychopharmacology has issued a consensus statement on evidence-based treatment of insomnia, parasomnias, and circadian rhythm disorders. Medscape Medical News (Source: Medscape Today Headlines)
Influence of genotype on dopamine transporter availability in human striatum and sleep architecture
Abstract: Genetic variants may modulate dopamine transporter (DAT) availability in the brain. A polymorphism within the intron 8 of the DAT1 gene was evaluated in 27 healthy men. No correlation between Int8 VNTR and either the inter-individual variability of the sleep architecture, or the DAT availability, as measured by single photon emission computed tomography (SPECT) and [99mTc]TRODAT-1 was observed. (Source: Psychiatry Research)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Excessive daytime sleepiness in depressed women
Abstract: Excessive daytime sleepiness (EDS) is a symptom with high public health importance. Within psychiatric settings, depression is the most significant risk factor for EDS; however, this relationship has not been clearly detailed. The aim of this study was to describe the quality of sleep of depressed patients with and without EDS and to investigate the association between EDS and depression severity. A cross-sectional study with 78 female depressed outpatients (34.17±11.37years; range 18?60) was performed. The Epworth Sleepiness Scale, the Athens Insomnia Scale, the Pittsburgh Sleep Quality Index, and the Hamilton Rating Scale for Depression (HRSD) were administered. Patients were classified in two groups: with (43.5%) and without (56.5%) EDS. There were no differences with regar...
Namibia: NBL Honours Eye Surgeon
Dr Helena Ndume is the Namibia Breweries Limited (NBL) Ambassador for the month of August - for almost single-handedly instituting a unique medical scheme which offers blind poverty-stricken Namibians eye surgery and intra-ocular lens implants free of charge. (Source: AllAfrica News: Health and Medicine)
Understanding the relationships between health outcomes in generalized anxiety disorder clinical trials
Conclusion&nbsp;&nbsp;This adapted Wilson?Cleary model for health outcomes validated in GAD should improve the understanding and usefulness of health status measurements in this condition and increase the applications of this model to other clinical trial data. Content Type Journal ArticleDOI 10.1007/s11136-010-9734-1Authors Kathleen W. Wyrwich, United BioSource Corporation, 7101 Wisconsin Ave. Suite 600, Bethesda, MD 20814, USANeesha Harnam, United BioSource Corporation, 7101 Wisconsin Ave. Suite 600, Bethesda, MD 20814, USAJulie C. Locklear, AstraZeneca Pharmaceuticals LP, Wilmington, Delaware USAHenrik Svedsäter, AstraZeneca R&D, Mölndal, SwedenDennis A. Revicki, United BioSource Corporation, 7101 Wisconsin Ave. Suite 600, Bethesda, MD 20814, USA Journal Quality o...
Chronic Insomnia With Objectively Measured Short Sleep Duration Is Associated With Increased Mortality In Men
A study in the Sept. 1 issue of the journal SLEEP found an elevated risk of death in men with a complaint of chronic insomnia and an objectively measured short sleep duration. The results suggest that public health policy should emphasize the diagnosis and appropriate treatment of chronic insomnia. Compared to men without insomnia who slept for six hours or more, men with chronic insomnia who slept for less than six hours were four times more likely to die during the 14-year follow-up period (odds ratio = 4.33)... (Source: Health News from Medical News Today)
Allergan Receives FDA Approval For LUMIGAN(R) 0.01% As First-Line Therapy Indicated For The Reduction Of Elevated Intraocular Pressure In Glaucoma
Allergan, Inc. (NYSE:AGN) announced the United States Food and Drug Administration (FDA) has approved LUMIGAN® (bimatoprost ophthalmic solution) 0.01% as a first-line therapy indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. LUMIGAN® 0.01% is an optimized reformulation of LUMIGAN® (bimatoprost ophthalmic solution) 0.03%. "The approval of LUMIGAN® 0... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Sleep-Deprived Teens Eat More Fat, Study Finds
Title: Sleep-Deprived Teens Eat More Fat, Study FindsCategory: Health NewsCreated: 9/1/2010 10:10:00 AMLast Editorial Review: 9/2/2010 (Source: MedicineNet Sleep General)
To
Title: To Not (Source: MedicineNet Sleep General)
Sleep-Deprived Teens Eat More Fat, Study Finds
Title: Sleep-Deprived Teens Eat More Fat, Study FindsCategory: Health NewsCreated: 9/1/2010 10:10:00 AMLast Editorial Review: 9/2/2010 (Source: MedicineNet Diabetes General)
Sleep-Deprived Teens Eat More Fat, Study Finds
Title: Sleep-Deprived Teens Eat More Fat, Study FindsCategory: Health NewsCreated: 9/1/2010 10:10:00 AMLast Editorial Review: 9/2/2010 (Source: MedicineNet Senior Health General)
Amaurosis after spine surgery: survey of the literature and discussion of one case
Abstract&nbsp;&nbsp;Postoperative vision loss (POVL) associated with spine surgery is a well known, albeit very rare complication. POVL incidence after spinal surgery ranges from 0.028 to 0.2%; however, due to the increase in number and duration of annual complex spinal operations, the incidence may increase. Origin and pathogenesis of POVL remain frequently unknown. A 73-year-old patient presented with lumbar disc herniation with associated neurological deficits after conservative pre-treatment at a peripheral hospital. Known comorbidities included arterial hypertension, moderate arterial sclerosis, diabetes mellitus type 2, mildly elevated blood lipids and treated prostate gland cancer. During lumbar spine surgery in modified prone position the patient presented with an acute episo...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Autoimmune disease in mothers with the FMR1 premutation is associated with seizures in their children with fragile X syndrome
In conclusion, autoimmune disease in carrier mothers was not associated with the presence of ASD in their children. However, seizures and tics were significantly increased in children of mothers with autoimmune disease. This suggests a potential new mechanism of seizure and tic exacerbation in FXS related to an intergenerational influence from autoimmunity in the carrier mother. Content Type Journal ArticleDOI 10.1007/s00439-010-0882-8Authors Weerasak Chonchaiya, Medical Investigation of Neurodevelopmental Disorders (MIND) Institute, University of California Davis Health System, 2825 50th Street, Sacramento, CA 95817, USAFlora Tassone, Medical Investigation of Neurodevelopmental Disorders (MIND) Institute, University of California Davis Health System, 2825 50th Street, Sacramento...
The developmental impact of prenatal stress, prenatal dexamethasone and postnatal social stress on physiology, behaviour and neuroanatomy of primate offspring: studies in rhesus macaque and common marmoset
Conclusions&nbsp;&nbsp;Perinatal stress-related environmental events exert short- and long-term effects on HPA function, behaviour and brain status in rhesus macaque and common marmoset. The mechanisms mediating the enduring effects remain to be elucidated, with candidates including increased basal HPA function and epigenetic programming. Content Type Journal ArticleDOI 10.1007/s00213-010-1989-2Authors Christopher R. Pryce, Behavioural Neurobiology Laboratory, Swiss Federal Institute of Technology Zürich, Schwerzenbach, SwitzerlandYves Aubert, Behavioural Neurobiology Laboratory, Swiss Federal Institute of Technology Zürich, Schwerzenbach, SwitzerlandClaudia Maier, Behavioural Neurobiology Laboratory, Swiss Federal Institute of Technology Zürich, Schwerzenbach, SwitzerlandP...
Increased risk of death in men with insomnia and a short sleep duration
Men with chronic insomnia who slept for less than six hours were four times more likely to die during the 14-year follow-up period, according to a new study. Results were adjusted for potential confounders such as body mass index, smoking status, depression and obstructive sleep apnea. Further adjustments for hypertension and diabetes had little effect on the elevated mortality risk. No significant mortality risk was found in women with insomnia and a short sleep duration of less than six hours. (Source: ScienceDaily Headlines)
Ketoprofen pharmacokinetics, efficacy, and tolerability in pediatric patients.
In conclusion, ketoprofen is effective and well tolerated in children for the control of post-surgical pain and for the control of pain and fever in inflammatory conditions. PMID: 20799760 [PubMed - in process] (Source: Paediatric Drugs)
New guidelines to ease sleepless nights
(SAGE Publications UK) Insomnia and other sleep disorders are very common, yet are not generally well understood by doctors and other health care professionals. Now the British Association for Psychopharmacology has released up-to-the-minute guidelines in the Journal of Psychopharmacology, published by SAGE, to guide psychiatrists and physicians caring for those with sleep problems. (Source: EurekAlert! - Medicine and Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Durezol® (Difluprednate Ophthalmic Emulsion 0.05%) Compared with Pred Forte® 1% Ophthalmic Suspension in the Treatment of Endogenous Anterior Uveitis
Journal of Ocular Pharmacology and Therapeutics , Vol. 0, No. 0. (Source: Journal of Ocular Pharmacology and Therapeutics)
Men who don't sleep may die sooner
HERSHEY, Pa., Sept. 1 (UPI) -- Men who complain of chronic insomnia and who sleep less than 6 hours a night have an increased risk of dying, U.S. researchers say. Insomnia - Sleep disorder - Health - Conditions and Diseases - United States (Source: Health News - UPI.com)
More sleep leads to more teen weight loss
BOSTON, Sept. 1 (UPI) -- A U.S. doctor suggests teens wishing to lose weight consider getting enough sleep -- 8 hours or more a night. Weight loss - Health - United States - Shopping - Support Groups (Source: Health News - UPI.com)
Sleep-deprived teenagers 'triple chances of mental illness' by spending nights online
Young people who rob themselves of sleep by spending all night surfing the internet and playing computer games are tripling their chances of developing a mental illness, according to research. (Source: Telegraph Health)
Too little sleep bad for teenagers' diets: study
CHICAGO (Reuters) - Teenagers who sleep less than eight hours a night on weeknights eat more fatty foods and snacks than those who get more than eight hours of sleep a night, U.S. researchers said on Wednesday. (Source: Reuters: Health)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Later school times lead to less snoring, more studying
With classes that start as early as 7 a.m. and buses that pull up long before sunrise, some 80 percent of American kids in grades 6 through 12 are falling short of sleep recommendations during the school year, according to research by the National Sleep... (Source: OrlandoSentinel: Medical Research)
Desperate for a Cure, One Physician Heals Himself
Frustrated by lack of interest from drug companies, a Belgian doctor pursues own research to help cure his myasthenia gravis, a rare neurological condition. (Source: WSJ.com: Health)
Online night-owls 'risk mental illness': Sleepless nights blamed for rise in teen depression
Young people who become sleep deprived by using the internet into the small hours are much more likely to become mentally ill in later life, research shows. (Source: the Mail online | Health)
Loving and Losing
Light blue eyes peered out at me from a fringe of dark lashes. "We were so perfect together, her sensuous smell, her dancing eyes, her exquisite face, her sumptuous body! She's so delicate, innocent, and I feel so protective with her." Mark was clearly smitten.I was curious about the nature of his ardor. "What else do you love about her?" I inquired."Caroline is so sweet, soft, feminine in her ways. We had this incredible spiritual and emotional connection. I don't get it. Why'd she end it?" Dreamy eyes turned into tortuous question marks.To which I posed yet another question. "What did she tell you?"Like all of you, Mark had all the answers, not me. "She said she needed to work on herself so she'd be more independent.":"I see." I commented.And he went on with "Here's the thing. There's th...
When Texting Becomes an Addiction
Excessive Texting Can Become Obession; Could Lead to Lack of Eating, Isolation and Sleep Deprivation (Source: Health News: CBSNews.com)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
When Texting Becomes an Addiction
Excessive Texting Can Become Obession; Could Lead to Lack of Eating, Isolation and Sleep Deprivation (Source: Health News: CBSNews.com)
Sleepy teens eat more fat: study
Teens who sleep less than eight hours on weeknights tend to eat more fatty foods than those who doze longer, researchers have found. (Source: CBC | Health)
To Not Sleep, Perchance to Shorten Your Life
Study finds insomniac men were more likely to die earlier (Source: The Doctors Lounge - Neurology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
When Texting Becomes an Addiction
Excessive Texting Can Become Obession; Could Lead to Lack of Eating, Isolation and Sleep Deprivation (Source: Health News: CBSNews.com)
To Not Sleep, Perchance to Shorten Your Life
Study finds insomniac men were more likely to die earlier Source: HealthDay Related MedlinePlus Pages: Men's Health, Sleep Disorders (Source: MedlinePlus Health News)
Are You a Texting Addict?
Excessive Texting Can Become Unhealthy Obession; Could Leads to Lack of Eating, Isolation and Sleep Deprivation (Source: Health News: CBSNews.com)
Less Than 5 Hours Sleep Linked To Higher Mental Illness Risk
Young healthy adults aged between 17 and 24 years who get less than an average of 5 hours' sleep each night have three times the risk of developing a mental illness compared to individuals of the same age who sleep eight to nine hours every night, according to a study carried out by the George Institute on Global Health, published in the medical journal Sleep. Researchers at the George Institute for Global Health carried out a survey involving 20,822 individuals aged 17-24 years across New South Wales, Australia, identified through the state vehicle licensing authority... (Source: Health News from Medical News Today)
Death risk from insomnia unclear
Conclusion This study has found that in middle-aged men, self-reported insomnia and objectively measured short sleep duration was associated with a greater risk of death during the 14-year follow-up period, compared with men who did not have insomnia or short sleep duration. However, these findings require careful interpretation and do not prove that insomnia increases the risk of early death: The study has an important limitation in that it is a secondary analysis of a study set up to assess the age distribution of people with sleep-disordered breathing. As such, the participants were not selected at random. All of them had a higher risk of sleep-disordered breathing, and the women had markedly higher BMIs. These factors may affect both mortality risk and insomnia. Therefore, the resul...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Back to school: college drinking concerns
It was recently reported that the University of New Hampshire is considering offering an amnesty program for underage students caught drinking on campus, in an effort to reduce alcohol related injury on school grounds. Those who support the program say students are drinking anyway, if the fear of suspension is removed they may be less inclined to be left alone when drunk, thereby reducing the risk of injury. Researchers at Children?s Hospital Boston disagree. A recently released study by the Children?s Center for Adolescent Substance Abuse Research (CeASAR) shows colleges with strictly enforced alcohol policies have fewer cases of underage drinking and dangerous binge drinking. Many young people are currently gearing up for an upcoming year at college. While at school it?s almost in...
Less is More: Study Shows That Teens Who Sleep Less Eat More Fatty Foods and Snacks
September 1, 2010 (EurekAlert) - A study in the Sept. 1 issue of the journal Sleep shows that teens who slept less than eight hours per weeknight ate higher proportions of fatty foods and snacks than adolescents who slept eight hours or more. The results suggest that short sleep duration may increase obesity risk by causing small changes in eating patterns that cumulatively alter energy balance, especially in girls. read more (Source: Diabetes News from dLife.com)
Sleep-Deprived Teens Eat More Fat, Study Finds
Those who get less than eight hours a night at risk for obesity, experts say (Source: The Doctors Lounge - Neurology)
The Detoxifier Found in Every Emergency Room
I want to tell you about something that could one day save your life. I recommend you keep some in your medicine cabinet at all times. Hospitals consider this so effective they carry it in emergency rooms to treat poison victims. Taken orally it has the ability to extract and neutralize many more times its own weight in gases, heavy metals, toxins, poisons, and other chemicals. Just a tiny amount the size of a postage stamp can absorb up to 4 tennis courts worth of toxins! It saves thousands of lives every year. But it does so much more. I?m talking about activated charcoal. Activated charcoal keeps poisons and toxins from being absorbed into your body. Taking activated charcoal can help wipe out decades of toxic heavy metals that may have been accumulating in your body. Harmful me...
Covidien Completes Sale Of Sleep Therapy Product Line
Covidien (NYSE: COV), a leading global provider of healthcare products, today announced that it has completed the previously announced sale of its Sleep Therapy continuous positive airway pressure (CPAP) and Bi-level products to PH Invest, a privately held company located in Luxembourg. Financial terms of the transaction were not disclosed... (Source: Health News from Medical News Today)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Sleep-Deprived Teens Eat More Fat
Those who get less than eight hours a night at risk for obesity, experts say Source: HealthDay Related MedlinePlus Pages: Obesity in Children, Sleep Disorders, Teen Health (Source: MedlinePlus Health News)
Insomnia and a short sleep duration
A study in the Sept. 1 issue of the journal SLEEP found an elevated risk of death in men with a complaint of chronic insomnia and an objectively measured short sleep duration. The results suggest that public health policy should emphasize the diagnosis and appropriate therapy of chronic insomnia........ (Source: Medicineworld.org: New Article Alert)
Supersymmetry - the end of the line | Jon Butterworth and Herbi Dreiner
Just before this blog moved to the Guardian, I wrote about a supersymmetry meeting I attended. Now my theory pal who organised it chips inIn case you missed it, I wrote about a conference on supersymmetry I went to last week, just before this blog moved home. I also gave some reasons why supersymmetry might, or might not, be seen as an attractive extension of the Standard Model of particle physics, given that there is no experimental evidence for it yet.Now my theory friend Herbi Dreiner, who I used to work with when I was a student and who organised the Bonn meeting, has given his view. Since I know there are heaps of supersymmetry fans out there, I thought I should bring it to your attention:The conference on "Supersymmetry and the Unification of Fundamental Interactions", which my coll...
Improving Ocular Disease Screening By LED Illumination Of The Eye
A new imaging system using six different wavelengths to illuminate the interior of the eyeball (ocular fundus) may pave the way for doctors to easily screen patients for common diseases of the eye, such as age-related macular degeneration and diabetic retinopathy. The system is described in the journal Review of Scientific Instruments, which is published by the American Institute of Physics... (Source: Health News from Medical News Today)
Renin-angiotensin-aldosterone system in patients with sleep apnoea: prevalence of primary aldosteronism
Obstructive sleep apnoea (OSA) is a sleep disorder characterized by recurrent episodes of oxygen desaturation during sleep, representing an independent risk factor for cardiovascular disease, such as myocardial infarction, stroke, congestive heart failure and resistant hypertension. Several neurohormonal mechanisms have been suggested to account for blood pressure increases, such as sympathetic nervous system hyperactivity, oxidative stress, renin&mdash;angiotensin&mdash;aldosterone system (RAAS) activation, endothelin system activation, and endothelial dysfunction. The aim of this study was to evaluate the behaviour of RAAS and the presence of primary aldosteronism (PA) in these patients and possible correlations between RAAS and the severity of OSA. From October 2007 to November 2008 we ...<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Being Hungry May Provide A Way To Stay Awake Without Feeling Groggy Or Mentally Challenged
As anyone who has ever struggled to keep his or her eyes open after a big meal knows, eating can induce sleepiness. New research in fruit flies suggests that, conversely, being hungry may provide a way to stay awake without feeling groggy or mentally challenged. Scientists at Washington University in St. Louis found that starvation allows the need for nourishment to push aside the need for sleep. Like humans and rats, fruit flies cannot survive without sleep... (Source: Health News from Medical News Today)
The Future of SLEEP at www.journalsleep.org
(Source: Sleep)
Sleep Homeostasis: Finding Odysseus among the Mnesteres
Commentary on Mongrain et al. Separating the contribution of glucocorticoids and wakefulness to the molecular and electrophysiological correlates of sleep homeostasis. SLEEP 2010;33:1147-1157. (Source: Sleep)
Metabolic Disease in Sleep Disordered Breathing: Puberty! Puberty!
Commentary on Kelly et al. Catecholamines, adiponectin, and insulin resistance as measured by HOMA in children with obstructive sleep apnea. SLEEP 2010;33:1185-1191. (Source: Sleep)
Short Sleep Duration Promoting Overconsumption of Food: A Reward-Driven Eating Behavior?
Commentary on Weiss et al. The association of sleep duration to adolescents&rsquo; fat and carbohydrate consumption. SLEEP 2010;33:1201-1209. (Source: Sleep)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Short Sleep Duration in Prevalent and Persistent Psychological Distress in Young Adults: The DRIVE Study
Conclusions: Self-reported shorter sleep duration is linearly associated with prevalent and persistent psychological distress in young adults. In contrast, only the very short sleepers had a raised risk of new onset of distress. Different approaches to sleep duration measurement yield different results and should guide any interventions to improve subjective sleep duration in young adults. Keywords: Sleep, psychological distress, cohort, young adult (Source: Sleep)
Separating the Contribution of Glucocorticoids and Wakefulness to the Molecular and Electrophysiological Correlates of Sleep Homeostasis
Conclusions: Our findings indicate that corticosterone contributes to the sleep-deprivation&ndash;induced changes in brain transcriptome that have been attributed to wakefulness per se. The study identified 78 transcripts that respond to sleep loss independent of corticosterone and time of day, among which genes involved in neuroprotection prominently feature, pointing to a molecular pathway directly relevant for sleep function. Keywords: Sleep regulation, corticosterone, neuroprotection, microarray, microRNA (Source: Sleep)
Insomnia with Short Sleep Duration and Mortality: The Penn State Cohort
Conclusions: Insomnia with objective short sleep duration in men is associated with increased mortality, a risk that has been underestimated. Keywords: Insomnia, short sleep duration, mortality, population-based study (Source: Sleep)
Determining Sleep Quality in Children with Sleep Disordered Breathing: EEG Spectral Analysis Compared with Conventional Polysomnography
Conclusions: Both conventional scoring and EEG spectral analysis indicated only minor disruptions to sleep quality in children with SDB when assessed across the night, in any specific hour of the night, or in any specific sleep stage. These results suggest that reduced daytime functioning previously reported in children with SDB may not be due to sleep disruption. We speculate that in children, in contrast to adults, a stronger sleep drive may preserve sleep quality even in severe SDB. Keywords: Pediatric, children, sleep, apnea, sleep quality, spectral analysis, EEG (Source: Sleep)
The Relative Impact of Obstructive Sleep Apnea and Hypertension on the Structural and Functional Changes of the Thoracic Aorta
Conclusions: Hypertension is a common finding in male AMI patients with OSA. In these patients, increased afterload from systemic hypertension rather than mechanical stress on the aortic wall determines the thoracic aortic size and abnormalities in aortic functional indices. BMI and age were also independent predictors of thoracic aortic dilatation. Keywords: Obstructive sleep apnea, hypertension, aortic root dilatation, acute myocardial infarction (Source: Sleep)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Obstructive Sleep Apnea and Aging Effects on Macrovascular and Microcirculatory Function
Conclusions: In obesity, both OSA and aging impair endothelial function and increase arterial stiffness. The influence of OSA on vascular function is most pronounced in young subjects. OSA, therefore, may be associated with functional impairment (&ldquo;a premature aging effect&rdquo;) on the endothelium and on arterial stiffness (in men), although skin microcirculatory function appears preserved. Keywords: Sleep, lung, breathing, vascular, apnea, airway, hypoxemia (Source: Sleep)
Catecholamines, Adiponectin, and Insulin Resistance as Measured by HOMA in Children with Obstructive Sleep Apnea
Conclusions: In obese pubertal children, OSA was associated with worse insulin resistance. Worsening OSA was associated with lower adiponectin and increasing urinary catecholamines. Whether OSA directly lowers adiponectin and aggravates a predisposition to insulin resistance is unknown, but these preliminary findings highlight the importance of further studying pediatric OSA. Keywords: Obstructive sleep apnea, insulin resistance, adiponectin, pediatrics (Source: Sleep)
Consequences of Comorbid Sleep Apnea in the Metabolic Syndrome&mdash;Implications for Cardiovascular Risk
Conclusion: Patients with MetSyn and comorbid OSA have higher BP, higher sympathetic drive, and diminished BRS, compared with patients with MetSyn without OSA. These adverse cardiovascular and autonomic consequences of OSA may be associated with poorer outcomes in these patients. Moreover, increased BP and sympathetic drive in patients with MetSyn+OSA may be linked, in part, to impairment of baroreflex gain. Keywords: Cardiovascular risk, sleep apnea, metabolic syndrome, sympathetic activation, baroreflex control (Source: Sleep)
The Association of Sleep Duration with Adolescents&rsquo; Fat and Carbohydrate Consumption
Conclusion: Quantitative measures of macronutrient intake in adolescents were associated with objectively measured sleep duration. Short sleep duration may increase obesity risk by causing small changes in eating patterns that cumulatively alter energy balance. Keywords: Sleep duration, diet, obesity, adolescents, 24-hour food recall (Source: Sleep)
Insomnia Symptoms and Daytime Function in Stable Heart Failure
Conclusions: Insomnia symptoms are common in patients with stable heart failure and are associated with daytime symptoms and decrements in functional performance. Keywords: Depression, fatigue, heart failure, insomnia, quality of life, sleep (Source: Sleep)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Enhancing Slow Wave Sleep with Sodium Oxybate Reduces the Behavioral and Physiological Impact of Sleep Loss
Conclusions: Pharmacological enhancement of SWS with sodium oxybate resulted in a reduced response to sleep loss on measures of alertness and attention. In addition, SWS enhancement during sleep restriction appears to result in a reduced homeostatic response to sleep loss. Keywords: Slow wave sleep, sleepiness, attention, sleep deprivation, sodium oxybate (Source: Sleep)
Energy Expenditure is Affected by Rate of Accumulation of Sleep Deficit in Rats
Conclusion: The change in VdotO2 is affected by rate of accumulation of sleep deficit and not the total sleep loss accrued. Negative energy balance, observed during TSD, is strongly attenuated when brief daily sleep opportunities are available to rats (CSR), despite greater accumulated sleep deficit. Keywords: Body temperature, chronic sleep restriction, core sleep, energy balance, energy metabolism, oxygen uptake, sleep debt, total sleep deprivation (Source: Sleep)
The Injection of Hypocretin-1 into the Nucleus Pontis Oralis Induces either Active Sleep or Wakefulness Depending on the Behavioral State when it is Administered
Conclusions: The present data demonstrate that the behavioral state of the animal dictates whether active sleep or wakefulness is induced following the injection of hypocretin. Therefore, we suggest that hypocretin-1 enhances ongoing states of wakefulness and their accompanying patterns of physiologic activity and that hypocretin-1 is also capable of promoting active sleep and the changes in various processes that occur during this state. Keywords: Microinjection, orexin, wakefulness, REM sleep, nucleus pontis oralis (Source: Sleep)
Increased Disease Activity is Associated with Altered Sleep Architecture in an Experimental Model of Systemic Lupus Erythematosus
Conclusions: The sleep-recording data showed that, during the progress and severe phases of the disease (19 and 29 wks of age, respectively), sleep architecture is altered. According to these results, increased sleep fragmentation, disease activity, and pain sensitivity are features observed in these mice, similar to symptoms of SLE. Keywords: Antinuclear antibody, lupus, (NZB/NZW)F1 mice, pain, sleep recording (Source: Sleep)
Relationship Between Surface Facial Dimensions and Upper Airway Structures in Obstructive Sleep Apnea
Conclusions: This study demonstrates that there is a relationship between surface facial dimensions and upper airway structures in subjects with OSA. These findings support the potential role of surface facial measurements in anatomic phenotyping for OSA. Keywords: Obstructive sleep apnea, facial phenotype, upper airway structures, magnetic resonance imaging (Source: Sleep)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Assessing the Prioritization of Primary Care Referrals for Polysomnograms
Conclusion: In a public hospital, primary care patients were less likely to be referred for PSG compared to mammogram and endoscopy. Uninsured patients were more likely to be referred for PSG than those with private insurance. Further studies are needed to address the low PSG referral rates in high-risk populations. Keywords: Sleep apnea, primary care, referral, health care delivery, socioeconomic status (Source: Sleep)
Narcolepsy: A Clinical Guide
Edited by Goswami, M., Pandi-Perumal, S. R., Thorpy, M. J.; Humana Press, Springer, New York; 330 pages; $219.00 (Source: Sleep)
How insomnia 'can send men to an early grave' - But are women immune to the dangers?
According to a study, male insomniacs are far more likely to die prematurely than those who regularly get a good night's sleep. (Source: the Mail online | Health)
Contribution of adenosine related genes to the risk of depression with disturbed sleep
Abstract: Background: Most patients with major depression report problems in their sleep: insomnia, early morning awakenings and fatigue correlating with poor sleep quality. One of the key substances regulating sleep is adenosine. We hypothesized that variations in polymorphic sites of adenosine related genes may predispose to depression with sleep disturbances.Methods: We selected 117 single nucleotide polymorphisms from 13 genes and analyzed their association with depression and specific sleep problems (early morning awakenings and fatigue). Data were collected as part of the Health 2000 Study based on Finnish population and included 1423 adult subjects.Results: Our major finding herein was, among women, the association of SLC29A3 polymorphism rs12256138 with depressive disorder (p=0.000...
Symptoms and signs of the initial prodrome of bipolar disorder: A systematic review
Conclusions: The initial prodrome of BD is characterized by dysregulation of mood and energy. Because of the apparently low specificity of prodromal symptoms and signs of BD, it is currently neither possible nor advisable to predict the development of BD based solely on early phenomenology. More well-designed in-depth studies, including qualitative ones, are needed to characterize the initial bipolar prodrome. (Source: Journal of Affective Disorders)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Teens: Sleep Less, Eat More
(Ivanhoe Newswire) -- Here's one more reason to make sure your child is getting enough rest: Teenagers who don't get enough sleep eat more fatty foods and snacks. (Source: Medical Headlines From Ivanhoe.com)
Study links shorter sleep durations with greater risks of mental distress in young adults
(American Academy of Sleep Medicine) Results show a linear association between sleep durations of less than eight hours and psychological distress in young adults between 17 and 24 years of age. The risk of psychological distress increased by 14 percent for each hour of nightly sleep loss. Those sleeping less than six hours a night were twice as likely to be experiencing distress as average sleepers. Long sleep durations of more than nine hours showed no association with distress. (Source: EurekAlert! - Medicine and Health)
Study finds an increased risk of death in men with insomnia and a short sleep duration
(American Academy of Sleep Medicine) Men with chronic insomnia who slept for less than six hours were four times more likely to die during the 14-year follow-up period. Results were adjusted for potential confounders such as body mass index, smoking status, depression and obstructive sleep apnea. Further adjustments for hypertension and diabetes had little effect on the elevated mortality risk. No significant mortality risk was found in women with insomnia and a short sleep duration of less than six hours. (Source: EurekAlert! - Medicine and Health)
Less is more: Study shows that teens who sleep less eat more fatty foods and snacks
(American Academy of Sleep Medicine) Teens who slept less than eight hours on weeknights consumed 2.2 percent more calories from fats and 3 percent fewer calories from carbs than teens who slept eight hours or more. In secondary analyses stratified by sex, the results were significant among girls but not boys. Also, for each one-hour increase in sleep duration, the odds of consuming a high amount of calories from snacks decreased by an average of 21 percent. (Source: EurekAlert! - Medicine and Health)
New Moms Get Enough Sleep, Just Not Good Sleep
Contrary to popular belief, new mothers may often get a decent amount of sleep in their babies' first few months -- but it's not a good-quality sleep, a new study suggests. Reuters Health Information (Source: Medscape ObGyn and Womens Health Headlines)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Problems with combining esophagogastroduodenoscopy and colonoscopy to analyze risks of transient hypoxia from procedures in patients with risk factors for obstructive sleep apnea: a call for stratifying risks according to individual procedures
Obstructive sleep apnea is increasingly being diagnosed, and its cardiopulmonary risks are being increasingly elucidated, but the risks of GI endoscopy in patients with obstructive sleep apnea is previously unstudied. Thus the article by Khiani et al related to this subject is particularly welcomed and important. Khiani et al show no significant difference in the rates of transient hypoxia between relatively high-risk and relatively low-risk groups for obstructive sleep apnea. I have 2 comments about this article. First, the authors analyze patients at relatively high risk of obstructive sleep apnea but exclude patients with diagnosed obstructive sleep apnea and 2 other significant cardiopulmonary conditions, chronic obstructive pulmonary disease and congestive heart failure. Thus, their c...
Response
We greatly appreciate Dr Cappell's insights and discussion of the strengths and weaknesses of our study. Obstructive sleep apnea is a condition that deserves attention in patients undergoing endoscopy. In particular, there are an increasing number of patients with undiagnosed obstructive sleep apnea who are undergoing endoscopy. While Dr Cappell is correct in stating that the overall prevalence of diagnosed obstructive sleep apnea may be around 3% to 7%, it has been estimated that the overall prevalence of obstructive sleep apnea in the U.S. population is approximately 20% with approximately 90% of all obstructive sleep apnea being undiagnosed. This is an under-recognized disease. Because there is a lack of literature on the percentage of patients at high risk for obstructive sleep apnea w...
The attitudes to CPAP treatment inventory: development and initial validation of a new tool for measuring attitudes to CPAP treatment
(Source: Journal of Sleep Research)
Insomnia, Short Sleep Duration Linked to Mortality in Men
Insomnia with objective short sleep duration is related to an increased risk of mortality among men, according to research published in the Sept. 1 issue of SLEEP. (Source: Modern Medicine)
Small-Gauge Pars Plana Vitrectomy: A Report by the American Academy of Ophthalmology
Conclusions: The technological advances of small-gauge vitrectomy seem to afford visual benefit comparable with that seen with traditional 20-gauge surgery, with more rapid healing, less discomfort, and an acceptably low incidence of adverse events comparable with those observed with conventional 20-gauge vitrectomy. As surgical techniques evolve and clinical experience grows, continued close surveillance is necessary for an accurate assessment of complications.Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (Source: Ophthalmology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Ranibizumab and Stroke
We would like to thank Boyer et al. for addressing the safety issues in patients with neovascular age-related macular degeneration (AMD) on intravitreal ranibizumab. In their study, a total of 4300 subjects were enrolled in 2 cohorts. Cohort 1 subjects were randomized 1:1 as follows: those who received 0.3 mg ranibizumab/shot with 3 monthly loading doses and then as needed thereafter; and those who were on the same regimen but received 0.5 mg ranibizumab/shot. Cohort 2 subjects received 0.5 mg ranibizumab/shot without loading doses. The study did not have a control group in which ranibizumab was not used. The subjects were not as intensively treated as those in previous pivotal clinical studies, as cohort 1 and 2 subjects received an average of 4.6 and 3.6 shots during the 12-month study p...
Sleep Research Society Young Investigator Award
The deadline to submit nominations for all SRS Awards is Friday, September 17, 2010. Nominations may be sent via e-mail to ncekosh@srsnet.org or they can be mailed to the Sleep Research Society, Attn: Nick Cekosh, 2510 North Frontage Road, Darien, IL 60561. This award recognizes an outstanding research effort by a new investigator in the field of sleep research. The basis for evaluation of candidates is a single publication in a refereed journal. The candidate should be the first author; and the article must be published or officially accepted for publication by the application deadline. On the application deadline, the candidate must be within 7 years of obtaining a terminal degree. Exceptions to this criterion will be considered for those applicants who feel that extenuating circ...
Hungry flies ok with less sleep
There may be certain conditions under which animals can forgo sleep without serious consequences (Source: The Scientist)
Lack of effects on lymphocyte function from chronic topical ocular cyclosporine medication: a prospective study
Abstract (Source: Veterinary Ophthalmology)
The central motor conductivity of genioglossus in obstructive sleep apnea
(Source: Respirology)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Reevaluating Obstructive Sleep Apnea as a Risk Factor for Cerebrovascular Disease
Over the past quarter century, multiple studies have firmly established an association between obstructive sleep apnea syndrome (OSAS) and stroke. Case reports, case series, and case-control studies have demonstrated an ?70% prevalence of OSAS in stroke survivors. Furthermore, the severity of OSAS (Apnea Hypopnea Index [AHI] of >30/hour) is much higher in stroke patients than in controls. In many cases, the symptoms of OSAS precede the occurrence of stroke, suggesting a cause-and-effect relationship. (Source: Journal of Stroke and Cerebrovascular Diseases)
CASE STUDY: Diagnostic challenge: Myasthenia gravis in the emergency department
Abstract (Source: Journal of the American Academy of Nurse Practitioners)
Ocular leech infestation.
Authors: Dey R, Dey S A 67-year-old myopic man presented to the Ophthalmology Department of a teaching hospital in the mountainous state of Sikkim with complaints of red eye, ocular discomfort, and sensation of something moving in his right eye that lead to occasional visual blurring from the previous four days. His symptoms started after washing his face in a stream. Clinical diagnosis was a leech in the limbus of the right eye at the 12 o'clock position. Ocular leech infestation should be considered in a patient with a history of swimming or face washing in streams and lakes. Herein we report a case of ocular leech infestation that presented as red eye with intermittent blurring of vision in the affected eye, and discuss the differential diagnosis and clinical significance. PMID:...
Progression of low back and lower extremity pain in a cohort of patients with achondroplasia.
Conclusions Individuals with achondroplasia and symptomatic spinal stenosis often experience back pain, which may progress to lower extremity pain and debilitating consequences. A more thorough understanding of the progression of spatial pain characteristics and pain severity may aid clinical decision making regarding the optimal timing for intervention. PMID: 20809726 [PubMed - in process] (Source: Journal of Neurosurgery.Spine)
Maxillary, mandibular and chin advancement surgery for the treatment of obstructive sleep apnoea
Abstract (Source: Australian Dental Journal)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
Hypoxia-Inducible Factor-1 in Arterial Disease: A Putative Therapeutic Target.
Authors: Kasivisvanathan V, Shalhoub J, Lim CS, Shepherd AC, Thapar A, Davies AH Hypoxia-inducible factor-1 (HIF-1) is a nuclear transcription factor that is upregulated in hypoxia and co-ordinates the adaptive response to hypoxia by driving the expression of over 100 genes. In facilitating tissues to adapt to hypoxia, HIF-1 may have a role in reducing the cellular damage induced by ischaemia, such as that seen in peripheral arterial disease (PAD), or following acute ischaemic insults such as stroke and myocardial infarction. This therefore raises the possibility of HIF-1 modulation in such contexts to reduce the consequences of ischaemic injury. HIF1 has further been implicated in the pathogenesis of atherosclerosis, abdominal aortic aneurysm (AAA) formation, pulmonary hypertension an...
Sleep deprivation suppresses the increase of rapid eye movement density across sleep cycles
(Source: Journal of Sleep Research)
Continucare acquires sleep diagnostic centers
Continucare Corp. said its subsidiary acquired an operator of two sleep diagnostic centers in South Florida. (Source: bizjournals.com Health Care:Health Insurance headlines)
Continucare acquires sleep diagnostic centers
Continucare Corp. said its subsidiary acquired an operator of two sleep diagnostic centers in South Florida. (Source: bizjournals.com Health Care:Biotechnology headlines)
LEDs Illuminate Eye for Ocular Disease Screening
August 31, 2010 (EurekAlert)  - A new imaging system using six different wavelengths to illuminate the interior of the eyeball (ocular fundus) may pave the way for doctors to easily screen patients for common diseases of the eye, such as age-related macular degeneration and diabetic retinopathy. The system is described in the journal Review of Scientific Instruments, which is published by the American Institute of Physics. read more (Source: Diabetes News from dLife.com)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
An Overview of the Treatment of Tourette's Disorder and Tics
Journal of Child and Adolescent Psychopharmacology Aug 2010, Vol. 20, No. 4: 249-262. (Source: Journal of Child and Adolescent Psychopharmacology)
Association Between Antipsychotics and Body Mass Index When Treating Patients with Tics
Journal of Child and Adolescent Psychopharmacology Aug 2010, Vol. 20, No. 4: 277-281. (Source: Journal of Child and Adolescent Psychopharmacology)
What Are Bedbugs? Are They Dangerous? [Repost]
This article originally appeared on February 27, 2009. We are reposting it because of current concern about bedbugs. NEW YORK--Sleep tight and don't let the bedbugs bite? If only . The creepy critters have become such a nuisance here that the city council is mulling legislation that would establish a bedbug task force, ban the sale of used mattresses, train exterminators, and regulate mattress disposal. Just how infested is Gotham? According to the New York Daily News , there were 22,218 complaints to the city's 311 hotline about infestations of the blood-sucking hemipterans, a 34 percent jump since this time last year. [More] (Source: Scientific American - Official RSS Feed)
What Are Bedbugs? Are They Dangerous? [Re-post]
This article originally appeared on February 27, 2009. We are re-posting it because of current concern about bedbugs. NEW YORK--Sleep tight and don't let the bedbugs bite? If only . The creepy critters have become such a nuisance here that the city council is mulling legislation that would establish a bedbug task force, ban the sale of used mattresses, train exterminators, and regulate mattress disposal. Just how infested is Gotham? According to the New York Daily News , there were 22,218 complaints to the city's 311 hotline about infestations of the blood-sucking hemipterans, a 34 percent jump since this time last year. [More] (Source: Scientific American - Official RSS Feed)
The Neural Basis of the Depressive Self
Depression is actually defined by specific clinical symptoms such as sadness, difficulty to experience pleasure, sleep problems etc., present for at least two weeks, with impairment of psychosocial functioning. (Source: Disabled World)<div id="medworm"><p><b><i>MedWorm Message:</i></b> Register for <b><a href="http://www.medmatcha.com" target ="_self">MedMatcha, MedWorm's medical advertising network</a></b>, and receive $5 free advertising.</p></div>
In depression, it's the physical symptoms that carry heart risk
The loss of interest, ruminations of suicide and feelings of guilt and sadness that are the hallmarks of depression may be debilitating. But it is depression's physical warning signs -- fatigue, sleep disturbance and appetite changes -- that are the... (Source: OrlandoSentinel: Medical Research)
Can Parents Help College Students Too Much?
As school starts this week in our part of the country, three images of adolescence are banging together in my brain.First are the kids - bleery with sleep and looking like great, landlocked turtles - meandering down the sidewalks of our small town towards their first days in middle school.&nbsp;Second are the late adolescents - early adults - arriving with suitcases, boxes, and parents in tow to begin their college careers.&nbsp; Orientation begins in just over an hour, and the little diners in town have been crowded with families since early morning.Third are the incredibly mature - and sometimes wildly adolescent - young men and women I see on my video screen, interviewed about their experiences in Iraq, getting ready to listen to the President talking about how the first part of their l...
The neural basis of the depression
Depression is actually defined by specific clinical symptoms such as sadness, difficulty to experience pleasure, sleep problems etc., present for at least two weeks, with impairment of psychosocial functioning. These symptoms guide the doctor to make a diagnosis and to select antidepressant therapy such as drugs or psychotherapy........ (Source: Medicineworld.org: New Article Alert)
Defining Depression At The Neurobiological Level
Depression is actually defined by specific clinical symptoms such as sadness, difficulty to experience pleasure, sleep problems etc., present for at least two weeks, with impairment of psychosocial functioning. These symptoms guide the physician to make a diagnosis and to select antidepressant treatment such as drugs or psychotherapy. At least 40% of depressed patients actually benefit from antidepressant treatment, whereas 20-30% of patients may suffer from chronic depression that negatively impacts their quality of life... (Source: Health News from Medical News Today)





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